Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressorLigand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativityβ-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesisThe E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stabilityNon-destructive inhibition of metallofullerenol Gd@C(82)(OH)(22) on WW domain: implication on signal transduction pathwayIdentification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 geneProtein tyrosine kinase signaling during oocyte maturation and fertilizationThe tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injuryThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionp73 as a pharmaceutical target for cancer therapyDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolismRescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.YAP accelerates Aβ(25-35)-induced apoptosis through upregulation of Bax expression by interaction with p73.Cellular responses to Cisplatin-induced DNA damage.Cisplatin in cancer therapy: molecular mechanisms of actionYAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation.A gp130-Src-YAP module links inflammation to epithelial regeneration.The hippo pathway in heart development, regeneration, and diseasesc-Abl phosphorylation of ΔNp63α is critical for cell viabilitySerum Inter-α-inhibitor activates the Yes tyrosine kinase and YAP/TEAD transcriptional complex in mouse embryonic stem cells.c-Abl tyrosine kinase promotes adipocyte differentiation by targeting PPAR-gamma 2.The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human disease.Persistent inhibition of ABL tyrosine kinase causes enhanced apoptotic response to TRAIL and disrupts the pro-apoptotic effect of chloroquine.α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch.The Hippo-YAP pathway: new connections between regulation of organ size and cancer.YAP oncogene overexpression supercharges colon cancer proliferation.Cell-Autonomous and Non-cell-autonomous Function of Hox Genes Specify Segmental Neuroblast Identity in the Gnathal Region of the Embryonic CNS in DrosophilaThe emerging roles of YAP and TAZ in cancerTumour suppressor genes in chemotherapeutic drug response.The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domainTAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells.DNA damage response in cisplatin-induced nephrotoxicity.
P2860
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P2860
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@ast
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en-gb
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@nl
type
label
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@ast
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en-gb
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@nl
prefLabel
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@ast
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en-gb
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@nl
P2093
P921
P3181
P1433
P1476
Yap1 phosphorylation by c-Abl ...... enes in response to DNA damage
@en
P2093
Nina Reuven
Yaarit Adamovich
Yosef Shaul
P304
P3181
P356
10.1016/J.MOLCEL.2007.12.022
P407
P50
P577
2008-02-01T00:00:00Z