Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
about
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformationUpregulation of FOXM1 induces genomic instability in human epidermal keratinocytesChk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repairBRCAness: finding the Achilles heel in ovarian cancerFOXM1 confers acquired cisplatin resistance in breast cancer cellsPrognostic Value of FOXM1 in Patients with Malignant Solid Tumor: A Meta-Analysis and System ReviewDNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosisFOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistanceMechanism of cancer cell death induced by depletion of an essential replication regulatorX-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocketStructural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapyFragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2The emerging roles of forkhead box (Fox) proteins in cancerFOXM1, a typical proliferation-associated transcription factorDNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometryCheckpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.Cell cycle-dependent localization of CHK2 at centrosomes during mitosis.Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer.FOXM1 modulates cisplatin sensitivity by regulating EXO1 in ovarian cancerFOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patientsForkhead box M1 transcription factor: a novel target for cancer therapy.Loss of Forkhead box M1 promotes erythropoiesis through increased proliferation of erythroid progenitors.Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence.Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometryPro-proliferative FoxM1 is a target of p53-mediated repression.Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage.Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma.Genomic scan reveals loci under altitude adaptation in Tibetan and Dahe pigs.B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cellsGenome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapyCHK2 kinase in the DNA damage response and beyondSorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1.Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphomaThe role of insulin-like growth factor-I in the physiopathology of hearing.Foxm1 mediates LIF/Stat3-dependent self-renewal in mouse embryonic stem cells and is essential for the generation of induced pluripotent stem cellsERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer.Activation of checkpoint kinase 2 is critical for herpes simplex virus type 1 replication in corneal epitheliumFOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells.Basal cell carcinomas: attack of the hedgehog.
P2860
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P2860
Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Chk2 mediates stabilization of ...... expression of DNA repair genes
@ast
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en-gb
Chk2 mediates stabilization of ...... expression of DNA repair genes
@nl
type
label
Chk2 mediates stabilization of ...... expression of DNA repair genes
@ast
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en-gb
Chk2 mediates stabilization of ...... expression of DNA repair genes
@nl
prefLabel
Chk2 mediates stabilization of ...... expression of DNA repair genes
@ast
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en-gb
Chk2 mediates stabilization of ...... expression of DNA repair genes
@nl
P2093
P2860
P921
P3181
P356
P1476
Chk2 mediates stabilization of ...... expression of DNA repair genes
@en
P2093
Pradip Raychaudhuri
Robert H Costa
Yongjun Tan
P2860
P304
P3181
P356
10.1128/MCB.01068-06
P407
P577
2007-02-01T00:00:00Z