Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
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Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substratesEvolutionary families of peptidasesBinding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitorBiochemical and functional analysis of the YME1 gene product, an ATP and zinc-dependent mitochondrial protease from S. cerevisiae.Structure of the human oxytocinase/insulin-regulated aminopeptidase gene and localization to chromosome 5q21Identification of zinc-binding ligands in the class II fructose-1,6-bisphosphate aldolase of Escherichia coliMutational analysis of aspartoacylase: implications for Canavan diseaseA novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursorMolecular cloning and expression of rat liver aminopeptidase BMolecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases.Structure, function, and regulation of leukotriene A4 hydrolase.Families of zinc metalloproteases.An unusual active site identified in a family of zinc metalloendopeptidasesSynaptobrevin/vesicle-associated membrane protein (VAMP) of Aplysia californica: structure and proteolysis by tetanus toxin and botulinal neurotoxins type D and F.Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis.Leukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296.Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378.Identification of glutamate residues essential for catalytic activity and zinc coordination in aminopeptidase A.Metal preferences of zinc-binding motif on metalloproteases.Molecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction.Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297.Leukotriene A4 hydrolase: a critical role of glutamic acid-296 for the binding of bestatin.Identification of glutamate-169 as the third zinc-binding residue in proteinase III, a member of the family of insulin-degrading enzymes.The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors.Probing the catalytic roles of n2-site glutamate residues in Escherichia coli glutamine synthetase by mutagenesis.Crystal structure of leukotriene A4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors.The human leukotriene A4 hydrolase gene is expressed in two alternatively spliced mRNA forms.A tyrosine residue essential for catalytic activity in aminopeptidase A.Detection of 5-lipoxygenase activity in the liverwort Marchantia polymorpha L.Analysis of the molecular mechanism of substrate-mediated inactivation of leukotriene A4 hydrolase.
P2860
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P2860
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
description
1991 nî lūn-bûn
@nan
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@ast
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en-gb
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@nl
type
label
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@ast
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en-gb
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@nl
prefLabel
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@ast
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en-gb
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@nl
P2093
P2860
P356
P1476
Leukotriene A4 hydrolase: dete ...... mutagenesis and zinc analysis
@en
P2093
A Wetterholm
B L Vallee
J F Medina
J Z Haeggström
P2860
P304
P356
10.1073/PNAS.88.17.7620
P407
P577
1991-09-01T00:00:00Z