Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1Lifestyle-related factors in predementia and dementia syndromesVitamin A and Alzheimer's diseaseTREM2 Variants in Alzheimer's DiseasePresenilin 1 is linked with gamma-secretase activity in the detergent solubilized stateBehavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient miceThe genetic epidemiology of neurodegenerative disease.Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcriptionAutosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor proteinThe familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta productionMetalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signalingSEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide productionHuntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzymeInteraction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer diseaseAnalysis of transcriptional modulation of the presenilin 1 gene promoter by ZNF237, a candidate binding partner of the Ets transcription factor ERMPresenilin 1 associates with glycogen synthase kinase-3beta and its substrate tauGeneration of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavageRole of presenilin 1 in structural plasticity of cortical dendritic spines in vivoThe Mdm2 oncoprotein interacts with the cell fate regulator NumbA scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinaseThe presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residueAlzheimer disease: new concepts on its neurobiology and the clinical role imaging will playPathways towards and away from Alzheimer's diseaseSelective inhibition of Alzheimer disease-like tau aggregation by phenothiazinesThe gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sampleHydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineagesEnhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the networkCurcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryAnalysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia riskFour decades of neurodegenerative disease research: how far we have come!Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11Evolutionary relationships among G protein-coupled receptors using a clustered database approachThe neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer diseaseNeurotransmitter receptors in the life and death of oligodendrocytesInteraction of presenilins with the filamin family of actin-binding proteinsA novel mechanism for the regulation of amyloid precursor protein metabolismPhosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis
P2860
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P2860
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@ast
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en-gb
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@nl
type
label
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@ast
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en-gb
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@nl
prefLabel
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@ast
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en-gb
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@nl
P2093
P921
P3181
P356
P1433
P1476
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
@en
P2093
E A Rogaeva
E I Rogaev
G Levesque
H A Da Silva
P2888
P304
P3181
P356
10.1038/375754A0
P407
P577
1995-06-29T00:00:00Z
P6179
1007185513