Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption
about
Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice siteGalactose toxicity in animalsThe role of enterocyte defects in the pathogenesis of congenital diarrheal disordersRenal sodium glucose cotransporter 2 inhibitors as a novel therapeutic approach to treatment of type 2 diabetes: Clinical data and mechanism of actionA missense mutation in the OCTN2 gene associated with residual carnitine transport activityThe K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosumCongenital hypothyroidism caused by a mutation in the Na+/I- symporterCorrection of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effectsCloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.Na+-to-sugar stoichiometry of SGLT3.Three surface subdomains form the vestibule of the Na+/glucose cotransporter SGLT1.Empagliflozin: a new sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum.Employing Escherichia coli to functionally express, purify, and characterize a human transporterExome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidusNatural variation in human membrane transporter genes reveals evolutionary and functional constraintsQuantitative PCR tissue expression profiling of the human SGLT2 gene and related family members.The molecular and genetic base of congenital transport defectsGlucose Galactose Malabsorption complicated with Rickets and Nephrogenic Diabetes Insipidus.Bridging the gap between structure and kinetics of human SGLT1.Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive DeficiencyBreath Hydrogen as a Biomarker for Glucose Malabsorption after Roux-en-Y Gastric Bypass Surgery.Identification of a disulfide bridge linking the fourth and the seventh extracellular loops of the Na+/glucose cotransporterConformational changes couple Na+ and glucose transportThe iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter.New ways of thinking about (and teaching about) intestinal epithelial function.Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences.Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption.Inhibition of SGLT2: a novel strategy for treatment of type 2 diabetes mellitus.Update on SLC26A3 mutations in congenital chloride diarrhea.SGLT2 inhibitors: a promising new therapeutic option for treatment of type 2 diabetes mellitus.Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences.Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.Five Arab children with glucose-galactose malabsorption.Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1.Functional expression of tagged human Na+-glucose cotransporter in Xenopus laevis oocytes.Distribution of glucose transporters in renal diseases.Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humansMolecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters.
P2860
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P2860
Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@ast
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en-gb
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@nl
type
label
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@ast
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en-gb
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@nl
prefLabel
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@ast
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en-gb
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@nl
P2093
P2860
P921
P356
P1433
P1476
Defects in Na+/glucose cotrans ...... lucose-galactose malabsorption
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0296-216
P407
P577
1996-02-01T00:00:00Z
P5875
P6179
1045214440