GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis
about
Identification and characterization of Hoxa9 binding sites in hematopoietic cellsRecent progress toward epigenetic therapies: the example of mixed lineage leukemiaMEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.Zebrafish hoxd4a acts upstream of meis1.1 to direct vasculogenesis, angiogenesis and hematopoiesisRole of HOXA9 in leukemia: dysregulation, cofactors and essential targetsmiR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemiaTaking a Bad Turn: Compromised DNA Damage Response in LeukemiaThe intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages.Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway.Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophagesActivating the Wnt/β-Catenin Pathway for the Treatment of Melanoma--Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferationEnriched transcription factor signatures in triple negative breast cancer indicates possible targeted therapies with existing drugs.CREB and leukemogenesis.Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.GSK-3α Is a Novel Target of CREB and CREB-GSK-3α Signaling Participates in Cell Viability in Lung Cancer.The pathogenesis of mixed-lineage leukemia.Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients.MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation.A Novel Glycogen Synthase Kinase-3 Inhibitor Optimized for Acute Myeloid Leukemia Differentiation Activity.Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.Epigenetic roles of MLL oncoproteins are dependent on NF-κBHaploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms.A cAMP and CREB-mediated feed-forward mechanism regulates GSK3β in polycystic kidney disease.TALE factors poise promoters for activation by Hox proteins.Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth.Menin as a hub controlling mixed lineage leukemia.Hox regulation of transcription: more complex(es)Mechanisms of mixed-lineage leukemia.Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseasesSynthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.Animal models of RLS phenotypes.Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.Insulin detemir enhances proglucagon gene expression in the intestinal L cells via stimulating β-catenin and CREB activities.PAR2-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells.
P2860
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P2860
GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@ast
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en-gb
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@nl
type
label
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@ast
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en-gb
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@nl
prefLabel
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@ast
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en-gb
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@nl
P2093
P2860
P3181
P1433
P1476
GSK-3 promotes conditional ass ...... transcription and oncogenesis
@en
P2093
Chenwei Lin
Christina Matheny
Kevin S Smith
Masayuki Iwasaki
Michael L Cleary
Stephen H K Wong
Zhong Wang
P2860
P304
P3181
P356
10.1016/J.CCR.2010.04.024
P407
P577
2010-06-01T00:00:00Z