Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
about
Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemiasTEL is a sequence-specific transcriptional repressorESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6The histone deacetylase 9 gene encodes multiple protein isoformsIsoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk geneCharacterization of NERF, a novel transcription factor related to the Ets factor ELF-1The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasiaIsolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets familyThe AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1The acetyltransferase 60 kDa trans-acting regulatory protein of HIV type 1-interacting protein (Tip60) interacts with the translocation E26 transforming-specific leukaemia gene (TEL) and functions as a transcriptional co-repressorThe inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesisEctopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemiaThe hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in cultureA domain shared by the Polycomb group proteins Scm and ph mediates heterotypic and homotypic interactionsModulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressorMN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in miceNative interface of the SAM domain polymer of TEL.Genomic profiling of B-progenitor acute lymphoblastic leukemiaPolymerization of the SAM domain of TEL in leukemogenesis and transcriptional repressionA mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemiaAML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoterStructure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT typeFusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)AML1 interconnected pathways of leukemogenesisThe many faces of SAMFamilial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid leukemiaYolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TELHematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factorCBFbeta is critical for AML1-ETO and TEL-AML1 activity.Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cells.Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature reviewPrevalence of ETV6/RUNX1 Fusion Gene in Pediatric Patients with Acute Lymphoblastic Leukemia in IranClinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemia: is there a tumor suppressor gene in chromosome 12p12.3?DNA copy number losses in human neoplasms.Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots.
P2860
Q22009417-A3628FF7-14EA-4708-9388-7926A189B698Q22010632-452FF3A9-F906-46D2-9426-9272694D02A6Q22011151-8B36AE48-5EE0-41BE-A6D7-AAFC26F1716CQ24290595-9A54085D-5E66-4B1E-873A-CB9DE7B43287Q24294872-7D9BAAC2-E44C-4F6E-96CF-E6087EEF07E4Q24309536-73F71BD7-99BF-4C85-8978-75A8B29A616BQ24316274-901935A6-0909-4B74-90D5-073096C05EDCQ24317100-2117C3D4-309E-4588-A315-1A97766EECFAQ24319000-8A6461BF-C036-4AC9-817A-77789AD0FD20Q24324229-045AF5DB-9F05-4C44-AD70-58399786088FQ24530158-F6467B70-7FE8-4343-A531-D3B45F97B416Q24554277-1BC5D839-12D8-4085-B899-8012171F8A66Q24567977-F45BC733-68EF-4F5E-9274-98916F6B560BQ24627258-D11DE332-F0C3-4EB7-9CB4-B50AB0AA1B8FQ24632107-4C625458-D6D6-4CEA-9E2F-83A9BD79A2A7Q24644206-2ECC1455-6F68-4B18-94F6-151CA2BAFA4BQ24648208-07DD18DB-DDE5-4312-9203-48E9EBABE4D7Q24650487-ABB97E12-5EA8-44CE-BDDB-AB024C05B85AQ24669642-95894703-EF4C-4BF7-B59E-F3BC597FE5D1Q24801634-2F7D756C-CD86-425C-A74F-32F2BAC520FDQ26829976-B9C0F831-975C-412D-BD0C-9929D27A4B37Q27633822-F3AA8328-D77A-45B4-A0D8-3C5E5C474835Q28141676-B6F4049D-3C03-41BC-A22C-2510BACDF40DQ28142631-8BC26F11-90EC-45F3-9FFB-14D54057AB0DQ28143157-661A4CAA-613B-497A-BA47-99CD381A21AFQ28145231-C1552F23-CE7D-4CEA-AC12-E14A3F537152Q28184349-4FB091E3-1610-4DDE-8EBD-DBEDFBA135CAQ28253873-92565F79-EE86-4DD8-B22F-84E8B418D369Q28254381-F0FFE50C-9694-491E-881D-DB6751290FD0Q28592571-1C35BFE3-08FE-4A0F-987B-6DD4BC5ED14AQ28594445-8C250AD4-6B35-465B-A829-267010610A32Q30439864-9FFD8248-D625-4A3B-8025-D83A7144967FQ30671189-C7B3BEDF-0A5A-4214-A48A-6428DF5360B4Q33187135-2AFFDBC3-794E-4C8C-89B9-5A691EADFADDQ33574980-2BEC0E90-E86F-491B-AE4E-3AAA03264BF3Q33628322-5BCB70D4-159D-4456-A735-F79F5D218A90Q33632230-AB275272-54C8-4D3A-ABA0-9595104B7868Q33706513-179B5410-9BBC-42BA-96A1-E3D2FAEA0EDBQ33733232-0FA9B05F-8F2E-427C-A7DE-7E1970506849Q33737642-B230BB4B-7989-41B0-89F6-8D5B10C686C6
P2860
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@ast
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en-gb
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@nl
type
label
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@ast
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en-gb
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@nl
prefLabel
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@ast
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en-gb
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@nl
P2093
P2860
P921
P3181
P356
P1476
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
@en
P2093
D G Gilliland
G F Barker
J D Rowley
P Bray-Ward
S C Raimondi
S K Bohlander
S W Hiebert
P2860
P304
P3181
P356
10.1073/PNAS.92.11.4917
P407
P577
1995-05-23T00:00:00Z