Translational homeostasis via the mRNA cap-binding protein, eIF4E
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Signalling to eIF4E in cancerThe Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual DysfunctionFolding of an intrinsically disordered protein by phosphorylation as a regulatory switchWhat Is the Impact of mRNA 5' TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?Overexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cellsInvestigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cellsEffects of Arginine concentration on the in vitro expression of Casein and mTOR pathway related genes in mammary epithelial cells from dairy cattleModelization of the regulation of protein synthesis following fertilization in sea urchin shows requirement of two processes: a destabilization of eIF4E:4E-BP complex and a great stimulation of the 4E-BP-degradation mechanism, both rapamycin-sensitiHypermethylated-capped selenoprotein mRNAs in mammals.Axonal cap-dependent translation regulates presynaptic p35.eIF4E is an important determinant of adhesion and pseudohyphal growth of the yeast S. cerevisiae.Deubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.The G32E functional variant reduces activity of PPARD by nuclear export and post-translational modification in pigsSDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis.Differential Requirements for eIF4E Dose in Normal Development and CancerTranslation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma.Cyclin B Translation Depends on mTOR Activity after Fertilization in Sea Urchin Embryos.Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells.PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stabilityInterleukin-10 inhibits lipopolysaccharide-induced tumor necrosis factor-α translation through a SHIP1-dependent pathway.Weighing up the possibilities: Controlling translation by ubiquitylation and sumoylation.Loss of Scribble Promotes Snail Translation through Translocation of HuR and Enhances Cancer Drug ResistanceDual modulation of Ras-Mnk and PI3K-AKT-mTOR pathways: A Novel c-FLIP inhibitory mechanism of 3-AWA mediated translational attenuation through dephosphorylation of eIF4E.Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers.Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2αNoninflammatory upregulation of nerve growth factor underlies gastric hypersensitivity induced by neonatal colon inflammation.Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney GrowthTranslation control during prolonged mTORC1 inhibition mediated by 4E-BP3.Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1)The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications.Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.Control of the negative IRES trans-acting factor KHSRP by ubiquitination.Proteasome modulates positive and negative translational regulators in long-term synaptic plasticity.CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis.Dual mTORC1/2 Inhibition as a Novel Strategy for the Resensitization and Treatment of Platinum-Resistant Ovarian CancerTranscriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes.Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencingThe novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression.Modulation of tumor eIF4E by antisense inhibition: A phase I/II translational clinical trial of ISIS 183750-an antisense oligonucleotide against eIF4E-in combination with irinotecan in solid tumors and irinotecan-refractory colorectal cancer.
P2860
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P2860
Translational homeostasis via the mRNA cap-binding protein, eIF4E
description
2012 nî lūn-bûn
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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-sg
2012年學術文章
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name
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@ast
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en-gb
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@nl
type
label
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@ast
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en-gb
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@nl
prefLabel
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@ast
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en-gb
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Translational homeostasis via the mRNA cap-binding protein, eIF4E
@en
P2093
Eigo Suyama
Hiroaki Imataka
Hironori Adachi
Pedro Aza-Blanc
Satoshi Mikami
Yuri V Svitkin
Ze'ev A Ronai
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2012.04.004
P407
P577
2012-06-29T00:00:00Z