P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
about
The lipid phosphatase activity of PTEN is critical for its tumor supressor functionThe tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionInteraction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinaseEvidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein functionPhosphorylation of the actin binding protein Drebrin at S647 is regulated by neuronal activity and PTENPIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexesA comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesA family of putative tumor suppressors is structurally and functionally conserved in humans and yeastPlatelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through AktProtein kinases and phosphatases in the control of cell fateProtean PTEN: form and functionProtein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transductionNegative regulation of PI 3-kinase by Ruk, a novel adaptor proteinA coding-independent function of gene and pseudogene mRNAs regulates tumour biologyIdentification of a PTEN-regulated STAT3 brain tumor suppressor pathwayRegulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayLoss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancerPtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migrationLoss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressorGenetic basis of Cowden syndrome and its implications for clinical practice and risk managementPTEN regulation of ERK1/2 signaling in cancerPhosphoinositides: tiny lipids with giant impact on cell regulationThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationGenetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITORPredicting everolimus treatment efficacy in patients with advanced endometrial carcinoma: a GINECO group study.Voltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function researchPTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flowPTEN associates with the vault particles in HeLa cellsPTEN is a protein tyrosine phosphatase for IRS1Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxisPTEN regulates cilia through Dishevelled.The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activityTargeting mutants of PTEN reveal distinct subsets of tumour suppressor functionsInhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cellsTPIP: a novel phosphoinositide 3-phosphataseNO signaling and S-nitrosylation regulate PTEN inhibition in neurodegenerationNovel germline mutations in the PTEN tumour suppressor gene found in women with multiple cancersPTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval development
P2860
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P2860
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@ast
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en-gb
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@nl
type
label
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@ast
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en-gb
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@nl
prefLabel
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@ast
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en-gb
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@nl
P2093
P2860
P3181
P356
P1476
P-TEN, the tumor suppressor fr ...... a dual-specificity phosphatase
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.94.17.9052
P407
P577
1997-08-01T00:00:00Z