Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity
about
The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activityAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneMolecular determinants of epidermal growth factor binding: a molecular dynamics studyNormal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glandsSingle-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate.Structure and function of epigen, the last EGFR ligand.Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy.Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands.Cell- and gene-specific regulation of primary target genes by the androgen receptor.Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat padTrafficking of epidermal growth factor receptor ligands in polarized epithelial cells.Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth.Rapid effects of LH on gene expression in the mural granulosa cells of mouse periovulatory follicles.Receptor-tyrosine-kinase-targeted therapies for head and neck cancer.Engineered bivalent ligands to bias ErbB receptor-mediated signaling and phenotypes.Heparin-binding EGF-like growth factor promotes epithelial-mesenchymal transition in human keratinocytes.Understanding cytokine and growth factor receptor activation mechanisms.ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas.Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology.Leucine-rich repeat and immunoglobulin domain-containing protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3).Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.Functional selectivity of EGF family peptide growth factors: implications for cancer.Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin.Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.Autocrine-derived epidermal growth factor receptor ligands contribute to recruitment of tumor-associated macrophage and growth of basal breast cancer cells in vivo.Biomarkers of drugs targeting HER-family signalling in cancer.Autocrine epidermal growth factor receptor ligand production and cetuximab response in head and neck squamous cell carcinoma cell lines.Neisseria gonorrhoeae-induced transactivation of EGFR enhances gonococcal invasion.PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth.A novel predictive strategy by immunohistochemical analysis of four EGFR ligands in metastatic colorectal cancer treated with anti-EGFR antibodies.Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid.EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.ErbB Receptors and Cancer.An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors.Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.EGFR signaling patterns are regulated by its different ligands.
P2860
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P2860
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@ast
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en-gb
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@nl
type
label
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@ast
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en-gb
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@nl
prefLabel
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@ast
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en-gb
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@nl
P2093
P2860
P921
P356
P1476
Epigen, the last ligand of Erb ...... ween affinity and mitogenicity
@en
P2093
Ayelet Di-Segni
Bose S Kochupurakkal
Daniel Harari
Eli Pikarsky
Gabriele Kerber
Galia Maik-Rachline
Ljuba Lyass
Raya Eilam
P2860
P304
P356
10.1074/JBC.M413919200
P407
P577
2004-12-17T00:00:00Z