Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
about
Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathwayCurrent concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatmentLoss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamicsMitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degenerationProcessing of optineurin in neuronal cellsEffects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cellsImpairment of protein trafficking upon overexpression and mutation of optineurin.The nerve growth factor signaling and its potential as therapeutic target for glaucomaCommon genetic determinants of intraocular pressure and primary open-angle glaucoma.Establishment of inducible wild type and mutant myocilin-GFP-expressing RGC5 cell linesFocus on molecular events in the anterior chamber leading to glaucoma.Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene.FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.Optineurin: The autophagy connection.Genes, pathways, and animal models in primary open-angle glaucoma.Cellular and molecular biology of optineurin.Myocilin and Optineurin: Differential Characteristics and Functional ConsequencesEffects of mutations and deletions in the human optineurin gene.The Outflow Pathway: A Tissue With Morphological and Functional Unity.Glaucoma pathogenesis and neurotrophins: Focus on the Molecular and Genetic basis for Therapeutic prospects.
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P2860
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
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2010 nî lūn-bûn
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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2010 թվականի հունվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@ast
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@ast
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@en-gb
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@nl
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Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@ast
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@en
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@en-gb
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@nl
P2093
P2860
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P3181
P1476
Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
@en
P2093
Beatrice Y J T Yue
Bum-Chan Park
Jeong-Seok Park
Rajalekshmy Shyam
Takahisa Koga
Xiang Shen
P2860
P304
P3181
P356
10.2353/AJPATH.2010.090194
P407
P577
2010-01-01T00:00:00Z