C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
about
Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153Mitochondria Retrograde Signaling and the UPR mt: Where Are We in Mammals?Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fateStress-induced C/EBP homology protein (CHOP) represses MyoD transcription to delay myoblast differentiationC/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic LesionsRole of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase.Systems genetics analysis of gene-by-environment interactions in human cellsMolecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis.Activation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells.A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitationActivating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression.Modeling interactions between Human Equilibrative Nucleoside Transporter-1 and other factors involved in the response to gemcitabine treatment to predict clinical outcomes in pancreatic ductal adenocarcinoma patients.Salubrinal promotes healing of surgical wounds in rat femurs.Asparagine synthetase: regulation by cell stress and involvement in tumor biologyA novel role for Tm7sf2 gene in regulating TNFα expressioneIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway.Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory ElementComparative Study on the Cellular and Systemic Nutrient Sensing and Intermediary Metabolism after Partial Replacement of Fishmeal by Meat and Bone Meal in the Diet of Turbot (Scophthalmus maximus L.).ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver.C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4ATF4-dependent transcription mediates signaling of amino acid limitation.Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.The transcription factor network associated with the amino acid response in mammalian cells.Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress.ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.Remodeling of lipid metabolism by dietary restriction of essential amino acidsGeneral control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression.The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression.Macrophage cell death and transcriptional response are actively triggered by the fungal virulence factor Cbp1 during H. capsulatum infection.Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cells.PERK-eIF2α-ATF4-CHOP signaling contributes to TNFα-induced vascular calcification.Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.A bifunctional intronic element regulates the expression of the arginine/lysine transporter Cat-1 via mechanisms involving the purine-rich element binding protein A (Pur alpha).The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation.A human XPC protein interactome--a resourceEffects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals.
P2860
0da50cfde9bf1493a6fab9938bba5a4aeaa6f28754cf7527b9918f114d8a66769e25fd791d88f6bb72ce94f3568420b4ab08b83da7fc55e48d36d4c78cc5100ec0f4809320e185432de73f811448ab01a3443f0ede29109f76396c24435b4f6f65c99829b4fe089b83ea7363f7d7cee9ecd1670ccaf5d995b8e85acea3ed012bff4b1434a737095edb57ed9ebea38c446f00335f7213601c5077adc241d8404ae3c49e3a7460c92c95174e472e1f7f768ea9b518f9050be401c61e55730d4a9981ffd05e35863654
P248
Q24312995-B72A8260-AD8A-4496-8587-1DD8883E759DQ26799891-11AF29CF-5483-425C-80E0-497EAAED2FA8Q26801543-F323B607-D4DB-4B25-B0AE-60DC80F97B7EQ28510649-6E1385FE-D9C4-4CB7-80A6-8BBDC7E3024FQ30359005-E14F33A9-926A-4A34-AC18-2B9937FA5550Q33682452-C96D2CC0-F55A-4BDA-8740-EFF86D17734CQ33708619-C666A62A-87FB-48E9-8BA2-CC9A047C55FBQ33963803-8C2D7C4A-56FC-4078-A429-3B57D2B5163CQ33976396-BD495536-447D-4CE6-B453-D760CC6B5BFAQ34107392-F972669C-490D-4FE2-ADB3-F14396653F01Q34170941-307081A7-6222-42D1-B36F-FEE69C9AABB9Q34234101-56B28C0D-0124-4E4C-B0D6-19CB9A50F2A1Q34275383-0ECA6B6E-266E-4321-9FA0-D0CEB81811E8Q34327474-1AB9F2A0-7755-41BD-91D0-B76DC6BB9B72Q34917960-934199F0-07A7-4101-A7C5-CCCE51DA849AQ35209983-C6624CFD-D912-49C6-AA09-716FECB8222CQ35379187-1F457619-43CA-44B4-9D56-8E83A507475FQ35860738-0399B082-9716-42F5-AC06-D286EDA360BFQ36179381-EA332F22-6511-48D8-814A-294046AF89A8Q36332920-3E752D59-8AD0-4F3F-B412-60BD8A805750Q36596344-BE422D4E-5985-4160-B12A-E2114531263FQ36597272-84C28663-84B3-46A3-9F04-AF296218E89FQ36655003-AE0943F4-A9F1-470B-AE25-948EEE02695CQ36716443-4ECB5DDE-69F5-41D6-9D26-939C9A6F7A49Q36830376-5EA35041-179E-41BD-B8ED-E2D113A42B63Q36849447-FFFA4C09-A0D4-4828-8694-4625985D4C90Q36934435-4DBEC4BF-F14D-4959-A942-A29B8EE9286BQ36954378-61D9F601-D5DC-47D8-AE31-CED22B68384FQ37031045-12F9CC13-088A-4D66-8462-24A31B5D3FF0Q37071811-52EA1ED6-CB76-4831-A135-5D1D11B1AB4FQ37132517-79BE9FA4-1D0A-429F-B9D2-9A577148A95EQ37148513-D597EB01-307E-4999-99AE-D8EBB91558E1Q37212506-2A8CA3AD-7A18-45C8-B25A-FB21D1A63E78Q37295559-7F2F4C7E-EA9F-4954-A3E5-922D6A2324C5Q37328721-285D0DF3-335E-4081-83E8-9473909F8BADQ37372007-DFD29231-97D2-4D91-B85A-B3A956957915Q37431928-24AD9CEF-4085-4A96-8F08-A01E52CEEA25Q37522950-62E2FEBA-0F7E-4E36-8B56-BF80D88BE9AAQ37535414-FD3F9C8C-5BD5-4B13-A65F-4615875F2653Q37973703-12776350-8195-4A2C-BB4D-B76721F740A9
P2860
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@ast
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en-gb
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@nl
type
label
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@ast
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en-gb
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@nl
prefLabel
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@ast
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en-gb
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@nl
P2860
P921
P3181
P356
P1476
C/EBP homology protein (CHOP) ...... the asparagine synthetase gene
@en
P2093
Michael S Kilberg
P2860
P304
P3181
P356
10.1074/JBC.M806874200
P407
P577
2008-12-12T00:00:00Z