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Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MSThe structure of human 15-lipoxygenase-2 with a substrate mimicRegulation of inflammation in cancer by eicosanoidsThe role of lipoxygenases in pathophysiology; new insights and future perspectivesConversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+ RegulationStructure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosaCrystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysisMammalian lipoxygenases and their biological relevanceRecent advances in the search for novel 5-lipoxygenase inhibitorsDeoxyhypusine hydroxylase from Plasmodium vivax, the neglected human malaria parasite: molecular cloning, expression and specific inhibition by the 5-LOX inhibitor zileutonDiscovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapyLipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoformsThe structural basis for specificity in lipoxygenase catalysis.Crystal structure of a lipoxygenase in complex with substrate: the arachidonic acid-binding site of 8R-lipoxygenase.Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection.Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancerRationally designed multitarget agents against inflammation and pain.Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesisDimerization of human 5-lipoxygenase.Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytesCellular protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity.Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism.Exploration of binding site pattern in arachidonic acid metabolizing enzymes, Cyclooxygenases and Lipoxygenases.Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to NanodiscsAnti-inflammatory trends of new benzimidazole derivatives.Identification and Characterization of a New Protein Isoform of Human 5-LipoxygenaseStructure and ligand based drug design strategies in the development of novel 5- LOX inhibitors.Locating a lipid at the portal to the lipoxygenase active siteIdentification of the Substrate Access Portal of 5-LipoxygenaseExploring N(1)-p-fluorobenzyl-cymserine as an inhibitor of 5-lipoxygenase as a candidate for type 2 diabetes and neurodegenerative disorder treatment.5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formationChemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol.Helical membrane protein conformations and their environmentFunctional characterization of genetic enzyme variations in human lipoxygenases.Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammationIron speciation in the cytosol: an overview.5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The structure of human 5-lipoxygenase
@ast
The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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type
label
The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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altLabel
The Structure of Human 5-Lipoxygenase
@en
prefLabel
The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
@en
The structure of human 5-lipoxygenase
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The structure of human 5-lipoxygenase
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P2093
P2860
P3181
P356
P1433
P1476
The structure of human 5-lipoxygenase
@en
P2093
Alan R Brash
David B Neau
Marcia E Newcomer
Maria T Waight
Nathaniel C Gilbert
Sue G Bartlett
William E Boeglin
P2860
P3181
P356
10.1126/SCIENCE.1197203
P407
P577
2011-01-14T00:00:00Z