CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
about
COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7AX-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesCCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDLCopper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancerMissense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndromeDNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesisProteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling.Functional understanding of the versatile protein copper metabolism MURR1 domain 1 (COMMD1) in copper homeostasis.Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development.News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1.Association between rs2294020 in X-linked CCDC22 and susceptibility to autoimmune diseases with focus on systemic lupus erythematosus.Copper metabolism domain-containing 1 represses the mediators involved in the terminal effector pathways of human labour and delivery.Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling.A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events.COMMD1: A Multifunctional Regulatory Protein.NDUFA4L2 is associated with clear cell renal cell carcinoma malignancy and is regulated by ELK1.CCDC22 gene polymorphism is associated with advanced stages of endometriosis in a sample of Brazilian women.COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexesCOMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complexGenome-wide association study identified new susceptibility loci for polycystic ovary syndrome.FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients.Endosomal Receptor Trafficking: Retromer and Beyond.Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.Structural insights into the architecture and membrane interactions of the conserved COMMD proteins
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P2860
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@ast
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en-gb
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@nl
type
label
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@ast
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en-gb
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@nl
prefLabel
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@ast
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en-gb
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@nl
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P1476
CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling
@en
P2093
Agnes Zecha
Andreas W Kuss
Baozhi Chen
Fiona J McDonald
Gabriel N Maine
Haiying Li
Iram W Zaidi
Mathew Wallis
Nathan Gluck
Petro Starokadomskyy
P2860
P304
P3181
P356
10.1172/JCI66466
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P577
2013-05-01T00:00:00Z