Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex
about
Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunitInteractions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes.LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesisTwo orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesisWDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ developmentCRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis.The nucleolar GTPase nucleostemin-like 1 plays a role in plant growth and senescence by modulating ribosome biogenesis.Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesisThe assembly factor Erb1 functions in multiple remodeling events during 60S ribosomal subunit assembly in S. cerevisiae.Nucleolar stress with and without p53.Transcriptional regulation of PES1 expression by c-Jun in colon cancer.5'-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decayNucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185.Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplicationPES1 promotes breast cancer by differentially regulating ERα and ERβ.The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.Critical role of nucleostemin in pre-rRNA processing.Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humansFunctional characterization of the ribosome biogenesis factors PES, BOP1, and WDR12 (PeBoW), and mechanisms of defective cell growth and proliferation caused by PeBoW deficiency in Arabidopsis.SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination.Nucleolar control of p53: a cellular Achilles' heel and a target for cancer therapy.Maize reas1 Mutant Stimulates Ribosome Use Efficiency and Triggers Distinct Transcriptional and Translational Responses.Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors.Pescadillo plays an essential role in plant cell growth and survival by modulating ribosome biogenesis.Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis.Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.Defects in 18 S or 28 S rRNA processing activate the p53 pathwayThe BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing.Rapid conditional knock-down-knock-in system for mammalian cells.The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword.Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner.The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly.Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interfaceComparative analysis of reference gene stability in human mesenchymal stromal cells during osteogenic differentiation.PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer.Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis.[Ribosomes synthesis at the heart of cell proliferation].
P2860
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P248
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P2860
Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex
description
2006 nî lūn-bûn
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2006 թուականին հրատարակուած գիտական յօդուած
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2006 թվականին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@ast
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en-gb
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@nl
type
label
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@ast
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en-gb
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@nl
prefLabel
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@ast
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en-gb
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Dominant-negative Pes1 mutants ...... oration into the PeBoW-complex
@en
P2093
Michael Hölzel
Thomas Grimm
Thomas Harasim
P2860
P304
P3181
P356
10.1093/NAR/GKL378
P407
P577
2006-01-01T00:00:00Z