TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3 - sprookjes - yvandenbroek - TriplyDB

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

http://www.wikidata.org/entity/Q24522833

about

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia Gradient of E2A activity in B-cell development.Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1 Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1 The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development SCL and associated proteins distinguish active from repressive GATA transcription factor complexes Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1 Aldehyde Dehydrogenases 1A2 Expression and Distribution are Potentially Associated with Neuron Death in Spinal Cord of Tg(SOD1*G93A)1Gur Mice.Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes.Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.Protein networks as logic functions in development and cancer.Transcriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL).Upstream distal regulatory elements contact the Lmo2 promoter in mouse erythroid cells Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells Comprehensive functional annotation of seventy-one breast cancer risk Loci.Physiological insights into all-trans-retinoic acid biosynthesis.Role of the GATA family of transcription factors in andrology.Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia.Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia Role of the GATA family of transcription factors in endocrine development, function, and disease Effect of lipid peroxidation products on the activity of human retinol dehydrogenase 12 (RDH12) and retinoid metabolism.Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia.The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.The molecular basis of T cell acute lymphoblastic leukemia

P2860

00a77473e0054b64ee0f9248829ebd7d443991a2 4941618453810280dcf65a0c41f76886f4d1dda8 65e8b754e07af0cfee02e0c9ea895a1449b1c373

P248

Q24300295-02316BF1-1F47-47C0-811F-B9C2C96E2D4E Q24319742-325443AA-9FA8-4D5E-80FF-841CA68CF2F6 Q24524018-177E2B67-B3D6-4FDF-85FF-4843452D4291 Q24554353-A49C053B-4C00-48E3-BB44-100E23E6B59E Q27316043-75FAB020-95E7-4A2F-988A-853E843F281E Q28215170-F2DA1E43-1BB0-4E80-A1A4-166026740B86 Q28508618-E66C5AE1-909A-41B3-8F09-C8EC7884FEA1 Q28510978-AB140EA9-E3CF-4D43-83FD-2B7FC80FA689 Q28576015-96635F95-2AF2-424C-9EB9-EE0863681301 Q28586811-EF2FFDE7-BA27-43B8-8B52-70965E623088 Q28589154-BA2B38F1-4509-434E-9A93-19EEE796D64B Q28591576-58885333-EFB5-4431-8205-21800C7010F0 Q28594530-05CFAB29-3372-4F83-842A-AFF6F4D00AF1 Q28594728-85BB21BE-7B4A-4861-9C14-2D1343988EE8 Q33717755-5C0A1580-C23C-45E6-9B9D-4CFC0E1AB010 Q33787320-5FB3FDBE-8358-402E-8673-8B3F7A4FFD89 Q33958544-7332AE3D-84AE-4127-916F-101A93F274E0 Q33985141-F416B0DC-389F-4A92-9725-7F07BB41296C Q34042616-BC517D8D-8959-43A0-882E-92CC811358D3 Q34358037-C1CE283E-C83D-4E43-B3D1-200A4FB90525 Q34534773-8C0B8CB3-3E1D-4238-952E-3CEEAC2D73FF Q34590410-C65898F5-B14C-4D71-9709-76514C618573 Q34684061-448B256B-BD39-4DD5-A997-924CD2B066EE Q34732289-C25AEC81-AD2D-463F-B659-8A9DE7202B08 Q34744860-CE10E2CD-2D78-40C4-940B-63A1CE4EA508 Q35230732-97161795-620D-4E3A-A2AD-307C7BEDF99E Q35821075-F29A877E-F9CE-4853-9FF9-19E9A811668A Q35849882-9387FEAB-AD47-49A8-9EB9-49E2D8910C06 Q36015211-51D8CC78-B262-489D-A49D-5B11C4609C54 Q36138840-F929F637-65F8-4A08-9EC6-626D808A44F1 Q36174127-0395013D-78BF-4343-A65C-5D733F9A48F3 Q36481117-B3546D81-156B-4532-882D-C984F6339C36 Q36494345-009E7A3A-740A-4C2B-94F0-BB374131D18B Q36512426-37F46BB1-F255-40B5-BF4B-E4BC2A833467 Q36742119-F606AA96-6670-4B7F-A5DC-3CF96B8A15F6 Q36914650-C448509C-A656-4608-9697-CEDA994DE5C0 Q37055532-A851062A-813E-4210-A14F-9244E042A7A1 Q37365555-DB06C900-6521-4B2C-BB13-B7AE6FE1EE77 Q37499781-66CEE751-8DC3-4A29-ACEE-89D55438AF86 Q38047834-4150C505-23AC-48E2-AEBE-F0A1E03E84BB

P2860

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

http://www.wikidata.org/entity/Q24522833

description

1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@ast

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en-gb

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@nl

type

label

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@ast

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en-gb

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@nl

prefLabel

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@ast

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en-gb

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@nl

P1433

Q24522833-154C4CB2-3ABD-47EB-8755-52B0B32F4A45

P1476

Q24522833-F859B43D-4B75-4038-858A-EECBA749B48C

P2093

Q24522833-186B3640-1EA5-441A-8C6B-8A474FF1E45F

Q24522833-BBC7581E-2F7E-4659-91BA-11EFED0C61AE

Q24522833-D802CF81-3745-43A5-9EF8-6E063E879716

P2860

Q24522833-08443007-4EB9-408B-8426-55649F4E61C1

Q24522833-0878C1F5-77A9-4912-B194-BD00B6B0E3B3

Q24522833-14D983AF-4CD1-499C-9526-4C8B3D0B8CC4

Q24522833-175DEB79-ABD7-46E9-BFB5-56592A4EB86A

Q24522833-1CD1E288-476D-47E3-B449-55858429083D

Q24522833-1E5BF3E4-D8DA-4631-A924-92B28B21B259

Q24522833-25F52D59-E744-45AE-ADCF-6E49FA28AB05

Q24522833-26084580-96BD-41BA-9ECD-AEDCF54FFAD0

Q24522833-32D34B46-5B40-4EDD-9415-D060117A646C

Q24522833-373AC8DD-72A2-4051-B7A9-2E4A64A6E82B

P304

Q24522833-A0AAB0CA-BF3C-4CCC-BC91-0F9911626949

P31

Q24522833-0B3107AE-ABBE-4E22-A599-C4E2F4B789A8

P3181

Q24522833-50180064-74B9-4650-BC38-A2CFFB24E04F

P356

Q24522833-085F503B-5B1B-4A1C-A0DC-60D6AF4487EE

P407

Q24522833-D510A646-E122-41C6-8696-F9BCAC3640AA

P433

Q24522833-7996066C-75CD-4F97-94A7-A0025B1CF190

P478

Q24522833-6968A396-DD30-481E-8CC8-B14231091C32

P577

Q24522833-8485D625-705E-45C1-95FA-FF313319EB8F

P698

Q24522833-9D5006B7-2D37-44D9-BDC8-C83CCFCAA5E9

P921

Q24522833-11053292-8AAB-4F34-9449-C1558956DB6E

Q24522833-11DE5403-FA6C-43DD-8857-FB106B3F85FD

Q24522833-15262215-0996-449A-96CD-6E452F0756C8

Q24522833-BAB7827C-DA57-4477-BA75-D21087BAB5B8

P932

Q24522833-6B9EB130-D9F7-4C49-B139-19E0EB244A25

P3181

P356

P1433

Molecular and Cellular Biology

P1476

TAL1 and LIM-only proteins syn ...... acting as cofactors for GATA3

@en

P2093

N Fukuhara

http://www.w3.org/2001/XMLSchema#string

O Yoshie

http://www.w3.org/2001/XMLSchema#string

Y Ono

http://www.w3.org/2001/XMLSchema#string

P2860

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)

The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

P304

6939-50

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3942587

http://www.w3.org/2001/XMLSchema#string

P356

10.1128/MCB.18.12.6939

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P577

1998-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

9819382

http://www.w3.org/2001/XMLSchema#string

P921

T cell acute lymphocytic leukemia 1

GATA binding protein 3

LIM domain only 1

P932

109277

http://www.w3.org/2001/XMLSchema#string