Protein kinase C and cyclic AMP-dependent protein kinase phosphorylate phospholemman, an insulin and adrenaline-regulated membrane phosphoprotein, at specific sites in the carboxy terminal domain
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Structure of the Na,K-ATPase regulatory protein FXYD1 in micellesCytoplasmic tail of phospholemman interacts with the intracellular loop of the cardiac Na+/Ca2+ exchangerRegulation of the cardiac sodium pumpHypertrophy, increased ejection fraction, and reduced Na-K-ATPase activity in phospholemman-deficient miceA separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscleExpression of phospholemman and its association with Na+-K+-ATPase in skeletal muscle: effects of aging and exercise trainingPhospholemman expression in extraglomerular mesangium and afferent arteriole of the juxtaglomerular apparatusAltered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exerciseIdentification of an endogenous inhibitor of the cardiac Na+/Ca2+ exchanger, phospholemmanRegulation of L-type calcium channel by phospholemman in cardiac myocytes.Phospholemman is a substrate for myotonic dystrophy protein kinase.Phospholemman deficiency in postinfarct hearts: enhanced contractility but increased mortality.Phospholemman and beta-adrenergic stimulation in the heart.Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation.Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPasePhospholemman does not participate in forskolin-induced swine carotid artery relaxation.Altered contractility and [Ca2+]i homeostasis in phospholemman-deficient murine myocytes: role of Na+/Ca2+ exchangePhospholemman overexpression inhibits Na+-K+-ATPase in adult rat cardiac myocytes: relevance to decreased Na+ pump activity in postinfarction myocytes.Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease.Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties.Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury.FXYD proteins: new tissue-specific regulators of the ubiquitous Na,K-ATPase.Phospholemman: a novel cardiac stress protein.Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm.The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation.Brain region-specific expression of Fxyd1, an Mecp2 target gene, is regulated by epigenetic mechanisms.FXYD proteins: new regulators of Na-K-ATPase.Phospholemman is not required for the acute stimulation of Na⁺-K⁺-ATPase α₂-activity during skeletal muscle fatigue.Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse.Phospholemman regulates cardiac Na+/Ca2+ exchanger by interacting with the exchanger's proximal linker domainFXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C.The isoelectric point, a key to understanding a variety of biochemical problems: a minireview.Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1.Induced overexpression of phospholemman S68E mutant improves cardiac contractility and mortality after ischemia-reperfusion.Na,K-ATPase regulation in skeletal muscle.Protein Interaction and Na/K-ATPase-Mediated Signal Transduction.Cytoplasmic targeting signals mediate delivery of phospholemman to the plasma membrane.Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPaseInhibition of insulin-stimulated phosphorylation of the intracellular domain of phospholemman decreases insulin-dependent GLUT4 translocation in streptolysin-O-permeabilized adipocytes.
P2860
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P2860
Protein kinase C and cyclic AMP-dependent protein kinase phosphorylate phospholemman, an insulin and adrenaline-regulated membrane phosphoprotein, at specific sites in the carboxy terminal domain
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@ast
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en-gb
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@nl
type
label
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@ast
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en-gb
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@nl
prefLabel
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@ast
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en-gb
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@nl
P2093
P2860
P356
P1433
P1476
Protein kinase C and cyclic AM ...... in the carboxy terminal domain
@en
P2093
P2860
P304
P356
10.1042/BJ3040635
P407
P478
304 ( Pt 2)
P577
1994-12-01T00:00:00Z