Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptors
about
Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasiaNeuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinaseUnique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2Gene expression markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)cbl-b inhibits epidermal growth factor receptor signalingHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorThe type 1 growth factor receptor family: new ligands and receptors and their role in breast cancer.Take your partners, please--signal diversification by the erbB family of receptor tyrosine kinases.Expression and function of EGF-related peptides and their receptors in gynecological cancer--from basic science to therapy.The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells.The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors.ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6.The ERBB3 receptor in cancer and cancer gene therapyerbB3 is an active tyrosine kinase capable of homo- and heterointeractions.Novel betacellulin derivatives. Separation of the differentiation activity from the mitogenic activity.Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells.Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems.AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors.Involvement of ERK1/2 signalling and growth-related molecules' expression in response to heat stress-induced damage in rat jejunum and IEC-6 cells.Epidermal growth factor receptor (EGFR) antibody down-regulates mutant receptors and inhibits tumors expressing EGFR mutations.SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells.Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites.Identification of an alternatively spliced mRNA transcript of human betacellulin lacking the C-loop of the EGF motif and the transmembrane domain.Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF.Regulation of heparin-binding EGF-like growth factor expression in Ha-ras transformed human mammary epithelial cells.Identification of betacellulin as a major peptide growth factor in milk: purification, characterization and molecular cloning of bovine betacellulin.New model of ErbB-2 over-expression in human mammary luminal epithelial cells.Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes.Analysis of heregulin symmetry by weighted evolutionary tracing.Development of pulmonary bronchiolo-alveolar adenocarcinomas in transgenic mice overexpressing murine c-myc and epidermal growth factor in alveolar type II pneumocytes.Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells.Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network.Disabling receptor ensembles with rationally designed interface peptidomimetics.Ras activation in human breast cancer.Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism.
P2860
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P2860
Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptors
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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type
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
@en-gb
Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
@ast
Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
@en
Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
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P2093
P2860
P356
P1433
P1476
Epidermal growth factor and be ...... ssed ErbB2 and ErbB3 receptors
@en
P2093
J H Pierce
M Alimandi
P2860
P304
P356
10.1093/EMBOJ/16.18.5608
P407
P577
1997-09-15T00:00:00Z