The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity - sprookjes - yvandenbroek - TriplyDB

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

http://www.wikidata.org/entity/Q24533177

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Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1 Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA Prep2: cloning and expression of a new prep family member Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module An autoinhibitory effect of the homothorax domain of Meis2 Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA-binding context.Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1 PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH HOXA9 regulates miR-155 in hematopoietic cells Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance Nuclear import of the transcription factor SHOOT MERISTEMLESS depends on heterodimerization with BLH proteins expressed in discrete sub-domains of the shoot apical meristem of Arabidopsis thaliana Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development.The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration Lock and key binding of the HOX YPWM peptide to the PBX homeodomain The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation TGIF2 interacts with histone deacetylase 1 and represses transcription HOXB13 homeodomain protein is cytoplasmic throughout fetal skin development The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors Subcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear export Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1 DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells.An Abd-B class HOX.PBX recognition sequence is required for expression from the mouse Ren-1c gene.Cooperative transcriptional activation by Klf4, Meis2, and Pbx1 Drosophila TGIF proteins are transcriptional activators.TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1.An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).Selective interaction of plant homeodomain proteins mediates high DNA-binding affinity.

P2860

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P2860

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

http://www.wikidata.org/entity/Q24533177

description

1998 nî lūn-bûn

@nan

1998 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի մարտին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

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name

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@ast

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en-gb

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@nl

type

label

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@ast

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en-gb

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@nl

prefLabel

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@ast

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en-gb

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@nl

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P1433

The EMBO Journal

P1476

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

@en

P2093

E Ferretti

http://www.w3.org/2001/XMLSchema#string

F Blasi

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F Mavilio

http://www.w3.org/2001/XMLSchema#string

J Berthelsen

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V Zappavigna

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P2860

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

Prep1, a novel functional partner of Pbx proteins.

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: clinical features and molecular pathogenesis

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

P304

1434-45

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scholarly article

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1766261

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10.1093/EMBOJ/17.5.1434

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P433

5

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P478

17

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P577

1998-03-02T00:00:00Z

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P5875

31992899

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P698

9482740

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P932

1170491

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