The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation
about
Gephyrin, the enigmatic organizer at GABAergic synapsesA single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domainsDisruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndromeLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.A locus for an auditory processing deficit and language impairment in an extended pedigree maps to 12p13.31-q14.3.The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesisUnder lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesActin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesThe inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cellsThe Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptorsPossible functional links among brain- and skull-related genes selected in modern humansForce-control at cellular membranesF-BAR family proteins, emerging regulators for cell membrane dynamic changes-from structure to human diseases.The BAR Domain Superfamily Proteins from Subcellular Structures to Human DiseasesSH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexesThe proposed functions of membrane curvatures mediated by the BAR domain superfamily proteins.Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalitiesCooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.Secretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sitesThe F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.Morphological and behavioral characterization of adult mice deficient for SrGAP3.Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis.Prefrontal-enriched SLIT1 expression in Old World monkey cortex established during the postnatal development.The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesisStructural plasticity: mechanisms and contribution to developmental psychiatric disordersCharacterization of a complex chromosomal rearrangement using chromosome, FISH, and microarray assays in a girl with multiple congenital abnormalities and developmental delayRegulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.Control of synapse development and plasticity by Rho GTPase regulatory proteins.ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain bindingReciprocal Relationship between Head Size, an Autism Endophenotype, and Gene Dosage at 19p13.12 Points to AKAP8 and AKAP8LBAR proteins in cancer and blood disordersA Novel Microduplication in the Neurodevelopmental Gene SRGAP3 That Segregates with Psychotic Illness in the Family of a COS ProbandActin Out: Regulation of the Synaptic Cytoskeleton.Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders.Rho-linked genes and neurological disorders.WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.Current knowledge of the large RhoGAP family of proteins.A-kinase anchoring proteins: from protein complexes to physiology and disease
P2860
Q21129486-20339248-1560-4B0B-B96F-599A33D599B7Q24328817-3E96C1CA-080F-45F6-9895-4A690968358EQ24337759-6646D1C5-88EF-46BF-B017-D8C9C0422DFFQ24550753-8336DA13-4732-40B2-9BA8-FCC4BC8EBD5FQ24596655-0DE6C50B-9674-48CA-8CF9-4C43F57FD2C5Q24654793-E5212C04-8F98-4419-94C9-891D7F5B569AQ27009455-59A8F281-7B0D-4B35-AA32-02EC5F0E2CCAQ28066333-9C6B4D87-6B92-436B-861F-05B1FEC8E0BFQ28487781-6FC2A9E7-9F31-47C7-BD4C-643400D00739Q28574269-9C45092A-A791-4D9B-8CDF-B372D76CE179Q28648399-93AB6ABA-4524-4593-B39D-2CA23EA75977Q28829680-5324AE76-C5E9-4BBC-BF40-B7C51F0699AAQ30009175-17C1EF16-CEC2-48BB-87F0-1C66E507E44EQ30010185-51C07DEA-5BD4-4ACB-AF51-50D33E7DEF2AQ30010197-76E8C9D9-08D9-4812-B8C5-51281AB0454BQ30156886-BFB63EA4-C234-416E-B1E7-7B95B0DD51B1Q30448529-51409DC5-D487-45B8-95AE-699C364742D5Q30498003-1B3179BE-596F-483C-835A-3F3F5DEB3CE1Q30513976-C0A26327-1383-474C-8E49-3D6A3A3E1DA3Q30529262-8C41E9A2-49DE-402F-B832-F6C23307967AQ30542623-E3F64F89-DE38-473C-AC83-14EA42F83DC6Q31096480-0B46952B-D2F0-42B3-9AB9-0D8B8F221333Q33927212-28A3E3CD-604E-4FE0-8C88-CCC0F57A92F8Q33928692-CCE3E8E7-3B82-4666-B2E4-DA81ED1654ADQ34116622-6E2AACB9-C8A8-440B-8D5D-5D1FE2C2CA01Q34317019-C231E4C6-19A0-4ED2-AD98-C65EFFECF3E5Q34442643-86F80476-5E57-4F45-B80F-BEC4F37BCA52Q34631519-789226B3-54D8-480D-B24A-F182FB85F38DQ34781600-C6E289CB-3631-431C-875D-DBE02D584C71Q35084942-CA41DB0B-2A98-4B29-BF6D-7C298686E628Q35651832-CEB0DF9F-6B88-416E-93C9-DE48BC8626F4Q35664162-6C13ACD0-821E-4666-8D0E-8015FFEB9C8CQ36073272-3EEF13FA-95FB-4EFF-B1B3-348AF2355B02Q36247979-FF4A2080-0040-45FF-872D-31D1861BC52DQ36323398-7A6B3D26-7D36-418D-8426-EFB34A62F7F7Q36444140-815A87A1-36D7-4652-8FDE-94C94E9A90ADQ36447580-77E76945-988E-4010-930E-A6DDFC1F0088Q36523177-B8FAF03B-1BFC-4228-872A-EA01DA33C52CQ36707513-4B2F0955-6D9E-45C7-9256-8BBF01318CAEQ37192490-86B8247A-7DE5-4CDA-99E8-1B035E9A0FAF
P2860
The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The novel Rho-GTPase activatin ...... e in severe mental retardation
@ast
The novel Rho-GTPase activatin ...... e in severe mental retardation
@en
The novel Rho-GTPase activatin ...... e in severe mental retardation
@nl
type
label
The novel Rho-GTPase activatin ...... e in severe mental retardation
@ast
The novel Rho-GTPase activatin ...... e in severe mental retardation
@en
The novel Rho-GTPase activatin ...... e in severe mental retardation
@nl
prefLabel
The novel Rho-GTPase activatin ...... e in severe mental retardation
@ast
The novel Rho-GTPase activatin ...... e in severe mental retardation
@en
The novel Rho-GTPase activatin ...... e in severe mental retardation
@nl
P2093
P2860
P3181
P356
P1476
The novel Rho-GTPase activatin ...... e in severe mental retardation
@en
P2093
Birgit Wogatzky
Dieter Karch
Dusan Bartsch
Farida Latif
Gholamali Tariverdian
Gudrun A Rappold
Malgorzata Zatyka
Stefan Kirsch
Uwe Leimer
Volker Endris
P2860
P304
11754-11759
P3181
P356
10.1073/PNAS.162241099
P407
P577
2002-08-23T00:00:00Z