A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability
about
Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure.Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeabilityTumor stiffness is unrelated to myosin light chain phosphorylation in cancer cellsCrosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal HyperpermeabilityParacellular drug absorption enhancement through tight junction modulationOccludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structureMyosin light-chain kinase is necessary for membrane homeostasis in cochlear inner hair cells.The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activation.Role of myosin light chain kinase in intestinal epithelial barrier defects in a rat model of bowel obstruction.Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestineNonmuscle myosin light chain kinase regulates murine asthmatic inflammationMLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier functionEpithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivoRole of the host defense system and intestinal microbial flora in the pathogenesis of necrotizing enterocolitis.Commensal bacterial endocytosis in epithelial cells is dependent on myosin light chain kinase-activated brush border fanning by interferon-γ.Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3.Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases.Epidermal growth factor protects the apical junctional complexes from hydrogen peroxide in bile duct epithelium.Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application.Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation.Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome.Myosin light chain kinase: pulling the strings of epithelial tight junction functionTranscriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro.Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitisTNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway.Mechanism of IL-1β modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activationSalvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis ModelRole of non-muscle myosin light chain kinase in neutrophil-mediated intestinal barrier dysfunction during thermal injuryTNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.Defining disease with laser precision: laser capture microdissection in gastroenterology.Fetal cholinergic anti-inflammatory pathway and necrotizing enterocolitis: the brain-gut connection begins in uteroA transgenic mouse with vascular endothelial over-expression of the non-muscle myosin light chain kinase-2 isoform is susceptible to inflammatory lung injury: role of sexual dimorphism and age.Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-alpha-induced regulation of myosin light chain kinase gene activity.AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function.Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity.Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.Cellular and molecular mechanism of interleukin-1β modulation of Caco-2 intestinal epithelial tight junction barrier.Regulation of paracellular permeability: factors and mechanisms.
P2860
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P2860
A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A differentiation-dependent sp ...... al tight junction permeability
@ast
A differentiation-dependent sp ...... al tight junction permeability
@en
A differentiation-dependent sp ...... al tight junction permeability
@nl
type
label
A differentiation-dependent sp ...... al tight junction permeability
@ast
A differentiation-dependent sp ...... al tight junction permeability
@en
A differentiation-dependent sp ...... al tight junction permeability
@nl
prefLabel
A differentiation-dependent sp ...... al tight junction permeability
@ast
A differentiation-dependent sp ...... al tight junction permeability
@en
A differentiation-dependent sp ...... al tight junction permeability
@nl
P2093
P2860
P3181
P356
P1476
A differentiation-dependent sp ...... al tight junction permeability
@en
P2093
Daniel R Clayburgh
Edwina D Witkowski
Fengjun Wang
Jerrold R Turner
Joe G N Garcia
John C Alverdy
Shari Rosen
Stephanie Blair
Steven Dudek
P2860
P304
P3181
P356
10.1074/JBC.M408822200
P407
P577
2004-12-31T00:00:00Z