Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein. - sprookjes - yvandenbroek - TriplyDB

Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.

Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.

http://www.wikidata.org/entity/Q24538727

about

US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrest Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1 Molecular basis for PKR activation by PACT or dsRNA The double-stranded RNA-binding protein, PACT, is required for postnatal anterior pituitary proliferation Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides Coronavirus gene 7 counteracts host defenses and modulates virus virulence Inhibition of Cellular 2'-5' Oligoadenylate Synthetase by the Herpes Simplex Virus Type 1 Us11 Protein Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development Vaccinia and other viruses with available vaccines show marked homology with the HIV-1 envelope glycoprotein: the prospect of using existing vaccines to stem the AIDS pandemic.Human Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway.Interferon-beta suppresses herpes simplex virus type 1 replication in trigeminal ganglion cells through an RNase L-dependent pathway Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli Assembly of an active translation initiation factor complex by a viral protein.In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation.Genetic metamorphosis of herpes simplex virus-1 into a biological therapeutic for human cancer.Activation and evasion of innate antiviral immunity by herpes simplex virus Herpesviruses and autophagy: catch me if you can!Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes.RNA binding properties of the US11 protein from four primate simplexviruses Neutralizing innate host defenses to control viral translation in HSV-1 infected cells.Nucleolin interacts with US11 protein of herpes simplex virus 1 and is involved in its trafficking Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.Varicella-Zoster virus IE63, a major viral latency protein, is required to inhibit the alpha interferon-induced antiviral response Viruses with deletions in antiapoptotic genes as potential oncolytic agents.Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus.To replicate or not to replicate: achieving selective oncolytic virus replication in cancer cells through translational control.The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress.Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.Biochemical analysis of PKR activation by PACT.ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element.Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs.Regulation of Innate Immune Responses by Bovine Herpesvirus 1 and Infected Cell Protein 0 (bICP0).G45R on nonstructural protein 1 of influenza A virus contributes to virulence by increasing the expression of proinflammatory cytokines in mice.

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P2860

Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.

http://www.wikidata.org/entity/Q24538727

description

2002 nî lūn-bûn

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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Inhibition of PACT-mediated ac ...... plex virus type 1 Us11 protein

@nl

Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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type

label

Inhibition of PACT-mediated ac ...... plex virus type 1 Us11 protein

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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prefLabel

Inhibition of PACT-mediated ac ...... plex virus type 1 Us11 protein

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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JVI.76.21.11054-11064.2002

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Journal of Virology

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Inhibition of PACT-mediated ac ...... lex virus type 1 Us11 protein.

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David Khoo

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Ganes C Sen

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Ian Mohr

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P2860

The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domain

PACT, a protein activator of the interferon-induced protein kinase, PKR.

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

Modular structure of PACT: distinct domains for binding and activating PKR

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

PKR; a sentinel kinase for cellular stress

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

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11054-11064

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136652

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