Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
about
Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humansAnalysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasiaLymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factorThe cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysisDevelopment of the mammalian lymphatic vasculatureVascular anomalies: from genetics toward models for therapeutic trialsA model for gene therapy of human hereditary lymphedemaGenetics of lymphatic anomaliesDoxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasisCharacterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis.Elevated expression of VEGFR-3 in lymphatic endothelial cells from lymphangiomasProliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristicsDermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema.Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos.Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.Signaling mechanisms in infantile hemangiomaFrom blue jeans to blue genes.The lymphatic system in health and disease.Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration.Lymphatic malformations: current cellular and clinical investigations.Current views on the function of the lymphatic vasculature in health and diseaseLymphatic versus blood vascular endothelial growth factors and receptors in humans.Lymphatic endothelium: a new frontier of metastasis research.Gastrointestinal lymphatics in health and diseasePathogenesis of vascular anomalies.Leukotriene B4 antagonism ameliorates experimental lymphedema.Aflibercept in the treatment of metastatic colorectal cancer.Update on the molecular genetics of vascular anomalies.AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation.When it comes to blocking lymphatics, it is all a question of timeClinical heterogeneity in lymphoedema-distichiasis with FOXC2 truncating mutations.Milroy disease and the VEGFR-3 mutation phenotype.Possible genetic predisposition to lymphedema after breast cancer.The new era of the lymphatic system: no longer secondary to the blood vascular systemPediatric lymphatic malformations: evolving understanding and therapeutic options.Albumin-binding domain conjugate for near-infrared fluorescence lymphatic imaging.mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.Novel Mechanisms of Compromised Lymphatic Endothelial Cell Homeostasis in Obesity: The Role of Leptin in Lymphatic Endothelial Cell Tube Formation and Proliferation
P2860
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P2860
Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@ast
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@en
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@nl
type
label
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@ast
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@en
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@nl
prefLabel
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@ast
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@en
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@nl
P2093
P2860
P3181
P356
P1476
Congenital hereditary lymphede ...... tivates VEGFR3 tyrosine kinase
@en
P2093
Devriendt K
Karkkainen MJ
P2860
P304
P3181
P356
10.1086/303019
P407
P577
2000-06-09T00:00:00Z