Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

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http://www.wikidata.org/entity/Q24542413
Q24547007
sameAs
The Crystal Structure of the Novobiocin Biosynthetic Enzyme NovP: The First Representative Structure for the TylF O-Methyltransferase SuperfamilyA crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyraseMarine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural productsAssessing sensitivity to antibacterial topoisomerase II inhibitors.Challenges of antibacterial discoveryMetabolic engineering for the production of natural products.Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.Biological activities of novel gyrase inhibitors of the aminocoumarin classCoumarin derivatives: an updated patent review (2012-2014).Synthesis, antimicrobial activity and molecular modeling study of substituted 5-aryl-pyrimido[5,4-c]quinoline-2,4-diones.Crystallization and preliminary X-ray analysis of the O-carbamoyltransferase NovN from the novobiocin-biosynthetic cluster of Streptomyces spheroides.Identification of inhibitors of Plasmodium falciparum RuvB1 helicase using biochemical assays.The Macromolecular Machines that Duplicate the Escherichia coli Chromosome as Targets for Drug Discovery.Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.
P2860

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

Item
http://www.wikidata.org/entity/Q24542413
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2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
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type
label
Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
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prefLabel
Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
@en
Structure-activity relationshi ...... by combinatorial biosynthesis
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Structure-activity relationshi ...... by combinatorial biosynthesis
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10.1128/AAC.50.4.1136-1142.2006
P407
P433
P478
P50
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P921
P932