Role of virus receptor Hyal2 in oncogenic transformation of rodent fibroblasts by sheep betaretrovirus env proteins
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IFITM proteins restrict viral membrane hemifusion.Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirusAmino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirusTransformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2Structural and functional comparisons of retroviral envelope protein C-terminal domains: still much to learnReceptor Binding and Low pH Coactivate Oncogenic Retrovirus Envelope-Mediated FusionCoevolution of endogenous betaretroviruses of sheep and their hostLung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repairA human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasionFunctional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.Membrane fusion and cell entry of XMRV are pH-independent and modulated by the envelope glycoprotein's cytoplasmic tailSheep retrovirus structural protein induces lung tumoursHuman RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence.Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activationJaagsiekte sheep retrovirus detected in human lung cancer tissue arrays.Jaagsiekte sheep retrovirus biology and oncogenesis.Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRVEmerging roles for hyaluronidase in cancer metastasis and therapy.Critical role of leucine-valine change in distinct low pH requirements for membrane fusion between two related retrovirus envelopes.Enhanced proliferation of primary rat type II pneumocytes by Jaagsiekte sheep retrovirus envelope protein.Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein.Fusogenicity of Jaagsiekte sheep retrovirus envelope protein is dependent on low pH and is enhanced by cytoplasmic tail truncations.Oncogenic transformation by the jaagsiekte sheep retrovirus envelope protein.Hyaluronidase 2 and its intriguing role as a cell-entry receptor for oncogenic sheep retroviruses.Enzootic nasal tumor virus envelope requires a very acidic pH for fusion activation and infection.Host species barriers to Jaagsiekte sheep retrovirus replication and carcinogenesis.Multiple domains of the Jaagsiekte sheep retrovirus envelope protein are required for transformation of rodent fibroblasts.Diagnosis and phylogenetic analysis of ovine pulmonary adenocarcinoma in China.Transformation of madin-darby canine kidney epithelial cells by sheep retrovirus envelope proteins.Expression and characterization of a soluble, active form of the jaagsiekte sheep retrovirus receptor, Hyal2.Jaagsiekte sheep retrovirus envelope efficiently pseudotypes human immunodeficiency virus type 1-based lentiviral vectors.Improved enzootic nasal tumor virus pseudotype packaging cell lines reveal virus entry requirements in addition to the primary receptor Hyal2.Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines.Jaagsiekte sheep retrovirus and enzootic nasal tumor virus promoters drive gene expression in all airway epithelial cells of mice but only induce tumors in the alveolar region of the lungs
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Role of virus receptor Hyal2 in oncogenic transformation of rodent fibroblasts by sheep betaretrovirus env proteins
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2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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name
Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
@ast
Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
@nl
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
@ast
Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
@en
Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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Role of virus receptor Hyal2 i ...... ep betaretrovirus env proteins
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A Dusty Miller
Fuh-Mei Duh
Michael I Lerman
Shan-Lu Liu
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P356
10.1128/JVI.77.5.2850-2858.2003
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2003-03-01T00:00:00Z