Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis - sprookjes - yvandenbroek - TriplyDB

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis

http://www.wikidata.org/entity/Q24561466

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Cancer as an evolutionary and ecological process Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq Teen smoking, field cancerization, and a "critical period" hypothesis for lung cancer susceptibility.Early events during neoplastic progression in Barrett's esophagus Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression Field cancerisation in colorectal cancer: a new frontier or pastures past?Lung cancer chemoprevention: current status and future prospects Genomic impact of cigarette smoke, with application to three smoking-related diseases Aberrant p53 expression in feline vaccine-associated sarcomas and correlation with prognosis High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence"DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry Pulmonary adenocarcinoma: a renewed entity in 2011 Lung cancer diagnosis from proteomic analysis of preinvasive lesions.Frequent expression of p53 protein without mutation in the atypical epithelium of human bronchus.Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer Clinical implications and utility of field cancerization Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.Following mitochondrial footprints through a long mucosal path to lung cancer.Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells.Field cancerization, clonality, and epithelial stem cells: the spread of mutated clones in epithelial sheets.TP53 mutations in human cancers: origins, consequences, and clinical use Effects of cigarette smoke on the human oral mucosal transcriptome Smoking and lung cancer: the role of inflammation.Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer.The clonal origin and clonal evolution of epithelial tumours.Molecular and genetic aspects of lung cancer.Buccal microRNA dysregulation in lung field carcinogenesis: gender-specific implications Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis.A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma Field cancerization in non-small cell lung cancer: implications in disease pathogenesis.Passenger mutations as a marker of clonal cell lineages in emerging neoplasia A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma.Air pollution and cancer: biomarker studies in human populations.Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk.Polarization gating spectroscopy of normal-appearing duodenal mucosa to detect pancreatic cancer.A translational approach to lung cancer research: From EGFRs to Wnt and cancer stem cells.

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P2860

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis

http://www.wikidata.org/entity/Q24561466

description

1997 nî lūn-bûn

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1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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Journal of Clinical Investigation

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Widely dispersed p53 mutation ...... anism for field carcinogenesis

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A F Gazdar

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D M Ritchey

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F G La Rosa

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I I Wistuba

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Y E Miller

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A genetic model for colorectal tumorigenesis

Antioncogenes and human cancer.

Cancer. p53, guardian of the genome

Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin.

The multistep nature of cancer.

The incidence of second primary tumors in long-term survivors of small-cell lung cancer.

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells.

Specific sequences from the carboxyl terminus of human p53 gene product form anti-parallel tetramers in solution

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10.1172/JCI119748

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