Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms
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Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygenThe interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.Initial sequence of the chimpanzee genome and comparison with the human genomeComparative analysis of cancer genes in the human and chimpanzee genomes.Fixation of the human-specific CMP-N-acetylneuraminic acid hydroxylase pseudogene and implications of haplotype diversity for human evolutionRapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primatesDevelopmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expressionColloquium paper: uniquely human evolution of sialic acid genetics and biologyDefining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophilsGenetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.Siglecs and immune regulationTreatment of allergic asthma: modulation of Th2 cells and their responsesSIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomasSialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharidesMouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligandHuman-specific derived alleles of CD33 and other genes protect against postreproductive cognitive declineEffort required to finish shotgun-generated genome sequences differs significantly among vertebratesExplaining human uniqueness: genome interactions with environment, behaviour and cultureFunctionally important glycosyltransferase gain and loss during catarrhine primate emergenceHigh divergence in primate-specific duplicated regions: human and chimpanzee chorionic gonadotropin beta genesDivergence, demography and gene loss along the human lineage.Multifarious roles of sialic acids in immunity.Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels.Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation.Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes.Loss of Siglec expression on T lymphocytes during human evolution.Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cellsExpression of Siglec-11 by human and chimpanzee ovarian stromal cells, with uniquely human ligands: implications for human ovarian physiology and pathology.Siglec receptors impact mammalian lifespan by modulating oxidative stress.Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.Sialic acids and autoimmune disease.Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions.Glycobiology simplified: diverse roles of glycan recognition in inflammationA genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs.Basic and clinical immunology of SiglecsDisease consequences of human adaptation.Monoclonal antibody-induced cytokine-release syndrome.Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?Siglec-8 and Siglec-F, the new therapeutic targets in asthma.Associations of genetic polymorphisms of Siglecs with human diseases.
P2860
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P2860
Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms
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2004 nî lūn-bûn
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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Large-scale sequencing of the ...... olution by multiple mechanisms
@ast
Large-scale sequencing of the ...... olution by multiple mechanisms
@en
Large-scale sequencing of the ...... olution by multiple mechanisms
@nl
type
label
Large-scale sequencing of the ...... olution by multiple mechanisms
@ast
Large-scale sequencing of the ...... olution by multiple mechanisms
@en
Large-scale sequencing of the ...... olution by multiple mechanisms
@nl
prefLabel
Large-scale sequencing of the ...... olution by multiple mechanisms
@ast
Large-scale sequencing of the ...... olution by multiple mechanisms
@en
Large-scale sequencing of the ...... olution by multiple mechanisms
@nl
P2860
P356
P1476
Large-scale sequencing of the ...... olution by multiple mechanisms
@en
P2093
Elliott H Margulies
Takashi Angata
P2860
P304
P356
10.1073/PNAS.0404833101
P407
P577
2004-09-07T00:00:00Z