Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
about
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific mannerPromotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3Cortactin signalling and dynamic actin networksNPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated alleleCo-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formationNephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrinRoles of adaptor proteins in podocyte biologyCapping protein regulators fine-tune actin assembly dynamicsThe function of endocytosis in podocytesA Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeletonCD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-CblThe carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndromeNOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complexStructural characterization and mutational assessment of podocin - a novel drug target to nephrotic syndrome - an in silico approachEstablishment of Nephrin Reporter Mice and Use for Chemical ScreeningSlit diaphragms contain tight junction proteinsNephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomersFlotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylationMice deficient in alpha-actinin-4 have severe glomerular diseaseNephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signalingStructure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy.CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.CIN85/CMS family of adaptor molecules.Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy.Activation of adenosine 2A receptors preserves structure and function of podocytesSlipins: ancient origin, duplication and diversification of the stomatin protein familyInhibition of the TRPC5 ion channel protects the kidney filterNew perspectives on the renal slit diaphragm protein podocin.The glomerular transcriptome and a predicted protein-protein interaction network.An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.Identification of proteins that interact with podocin using the yeast 2-hybrid system.Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAsA disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocinA comprehensive analysis and annotation of human normal urinary proteome.Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography.Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review.NPHS2 variation in sporadic focal segmental glomerulosclerosis
P2860
Q24300368-1A55E1D3-47CD-4A29-9B69-B035C7FB8423Q24301742-4B9E1C3C-FC0A-4642-90CB-C044C0BB4923Q24528115-89212E95-BD1B-4737-A162-DE9583D479BDQ24554305-9B0121DC-AAB8-49AC-A760-2CC2EE734DABQ24669656-3E5FCE43-49A5-4B2B-AF09-9A9215080E49Q24670040-BF02BB84-2FF5-402D-8988-3F51C8927258Q26863721-81F40515-2DC4-4F1B-8BD1-E425345DA3BDQ27006034-0BBB101B-D460-47DC-A6B9-156DC851B7C1Q27006914-30B1DB25-3521-48EB-A376-A54E1858B3E2Q28188354-5A35B05A-FEA0-4B73-B163-D48EDD4D2CEAQ28206219-B18E2BBD-C2BA-48C5-9DA4-B4284B40CE9CQ28208445-28990135-4B9C-4854-A0D2-C0091F234AEAQ28256662-D29AE610-1668-46D2-956C-FFE6064A2496Q28296660-2F99C068-A890-400A-9B1E-E8D7C3AB008FQ28306636-1A7D60C8-7C4D-4610-AED6-6A34CB2C3DE5Q28552280-60E10C54-5093-4BAF-9B35-F469F2545840Q28573180-227F1055-2339-46C9-94DB-5638542C84B0Q28577451-3B2B1626-36BF-454B-96D8-C3BA23B60C3DQ28585115-7ECA3A0D-6C2A-4468-86C8-AFC59D19DF5CQ28593056-2CEBD52E-F88F-406B-9D3C-B7C8EC615122Q28611533-73F7CD62-BD68-40E8-BAEA-5317EE8DA2AEQ30009462-E1AAA892-39B5-4D72-9949-FDC3EACA29C3Q30157406-B201CDF1-72D3-4C62-A57F-FCDED07A02C5Q30159868-4EFF6562-175E-4AB9-BA44-00B1706FA867Q30165181-108B7D9E-D594-414B-97DB-B96912A8A72AQ30427148-3F45D33F-6C4E-4D67-8270-62DA47114E84Q30438880-BE84736F-7219-412B-858D-64C9E2C0828EQ30440549-0EC367FB-82E3-43EB-8D20-816F22F9DADDQ30481355-2E64409E-9F0E-44CB-A7A2-56C5DA06192FQ30559274-91BD7078-9476-489D-8272-891792D42FBBQ31005416-DCAEB742-D6BE-48D1-8B3C-7276618382FAQ33306795-38D72584-07ED-4B9D-A6F3-F2457928EAB4Q33399707-03CA9C31-BDDE-42EA-AF17-D7309DC85576Q33442842-1ABBF248-8CA6-4A5F-86B9-1B2FAD91E0CCQ33490128-9EEC7C51-561C-4D7E-8AC3-B518DF6B4046Q33676320-F9B91FC4-D585-4209-BC76-06493456AE37Q33780112-AE735EBD-0186-44A2-87F2-738448A7621AQ33844627-34F837F3-94ED-42B3-A806-DC44B04FB0D0Q33845904-94445FB5-F93E-49D4-B043-E7CBB12F9A31Q33897098-D7AE7083-08F0-4BD0-A55C-9BAD8F1C1811
P2860
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@ast
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@en
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@nl
type
label
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@ast
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@en
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@nl
prefLabel
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@ast
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@en
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@nl
P2093
P2860
P3181
P1476
Podocin, a raft-associated com ...... teracts with CD2AP and nephrin
@en
P2093
L B Holzman
M A Saleem
P2860
P304
P3181
P356
10.1172/JCI12849
10.1172/JCI200112849
P407
P577
2001-12-01T00:00:00Z