MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells - sprookjes - yvandenbroek - TriplyDB

MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells

MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells

http://www.wikidata.org/entity/Q24603505

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Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25 The P2X7 receptor is a key modulator of aerobic glycolysis MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta Recent advances in the molecular understanding of glioblastoma A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion Insights into the Regulatory Role of Non-coding RNAs in Cancer Metabolism MicroRNA in Metabolic Re-Programming and Their Role in Tumorigenesis Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Interplay Between Metabolism and Oncogenic Process: Role of microRNAs MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use MicroRNAs in cancer: glioblastoma and glioblastoma cancer stem cells Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects A genome-wide systematic analysis reveals different and predictive proliferation expression signatures of cancerous vs. non-cancerous cells Strategies of eradicating glioma cells: a multi-scale mathematical model with MiR-451-AMPK-mTOR control Life history trade-offs in cancer evolution TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma Micro-masters of glioblastoma biology and therapy: increasingly recognized roles for microRNAs.microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.The elephant in the room: do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?The role of microRNAs in glioma initiation and progression.The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation required.Selective release of microRNA species from normal and malignant mammary epithelial cells.The microRNA and messengerRNA profile of the RNA-induced silencing complex in human primary astrocyte and astrocytoma cells PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation.NDRG2 overexpression enhances glucose deprivation-mediated apoptosis in breast cancer cells via inhibition of the LKB1-AMPK pathway.MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes.miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: a mathematical model A novel miR-451a isomiR, associated with amelanotypic phenotype, acts as a tumor suppressor in melanoma by retarding cell migration and invasion MicroRNA-351 regulates TMEM 59 (DCF1) expression and mediates neural stem cell morphogenesis.Understanding the effects of tobacco smoke on the pathogenesis of aortic aneurysm.MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor.Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1.Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549).

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P2860

MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells

http://www.wikidata.org/entity/Q24603505

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@ast

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@en

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@nl

type

label

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@ast

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@en

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@nl

prefLabel

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@ast

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@en

MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@nl

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J.MOLCEL.2010.02.018

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MicroRNA-451 regulates LKB1/AM ...... tabolic stress in glioma cells

@en

P2093

E Antonio Chiocca

http://www.w3.org/2001/XMLSchema#string

Gerard Nuovo

http://www.w3.org/2001/XMLSchema#string

Jakub Godlewski

http://www.w3.org/2001/XMLSchema#string

James Van Brocklyn

http://www.w3.org/2001/XMLSchema#string

Jeff Palatini

http://www.w3.org/2001/XMLSchema#string

Michael C Ostrowski

http://www.w3.org/2001/XMLSchema#string

Michael De Lay

http://www.w3.org/2001/XMLSchema#string

Michal O Nowicki

http://www.w3.org/2001/XMLSchema#string

Sean E Lawler

http://www.w3.org/2001/XMLSchema#string

P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

AMPK phosphorylation of raptor mediates a metabolic checkpoint

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

The regulation of AMP-activated protein kinase by phosphorylation

A pharmacological activator of AMP-activated protein kinase (AMPK) induces astrocyte stellation.

Understanding the Warburg effect: the metabolic requirements of cell proliferation

MicroRNAs: target recognition and regulatory functions

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620-32

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scholarly article

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1549366

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10.1016/J.MOLCEL.2010.02.018

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5

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37

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Agnieszka Bronisz

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2010-03-12T00:00:00Z

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41942886

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20227367

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P921

metabolic adaptation

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3125113

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