The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5
about
Kinesin-5: cross-bridging mechanism to targeted clinical therapyLoop 5-directed compounds inhibit chimeric kinesin-5 motors: implications for conserved allosteric mechanismsLoop L5 acts as a conformational latch in the mitotic kinesin Eg5Analysis of the interaction of the Eg5 Loop5 with the nucleotide siteTPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule.The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5"Snapshots"of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.Directional switching of the kinesin Cin8 through motor coupling.A seesaw model for intermolecular gating in the kinesin motor proteinModel-independent decomposition of two-state dataThe loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5.Microtubule capture by mitotic kinesin centromere protein E (CENP-E).Kinesin tail domains are intrinsically disordered.The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5.Loop L5 assumes three distinct orientations during the ATPase cycle of the mitotic kinesin Eg5: a transient and time-resolved fluorescence study.Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity.Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.The yeast kinesin-5 Cin8 interacts with the microtubule in a noncanonical manner.Multiple conformations of the nucleotide site of Kinesin family motors in the triphosphate stateSrc family kinase phosphorylation of the motor domain of the human kinesin-5, Eg5.
P2860
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P2860
The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@ast
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@en
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@nl
type
label
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@ast
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@en
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@nl
prefLabel
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@ast
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@en
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@nl
P2093
P2860
P1433
P1476
The conserved L5 loop establis ...... on of the Kinesin-5 motor, eg5
@en
P2093
Adam G Larson
Edward Pate
Nariman Naber
Roger Cooke
Sarah E Rice
P2860
P304
P356
10.1016/J.BPJ.2010.03.014
P407
P577
2010-06-02T00:00:00Z