Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase
about
Limitin: An interferon-like cytokine that preferentially influences B-lymphocyte precursorsRantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cellsIdentification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptorA protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptorDifferences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptorPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinThe SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signalsKinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral stateNS5 of dengue virus mediates STAT2 binding and degradationFunctional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signalingThe amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptorJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activationDifferential Effects of Mutations in NS4B on West Nile Virus Replication and Inhibition of Interferon SignalingThe human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoproteinProtein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part IV)Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signalingThe type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor proteinInteraction of the transcriptional activator Stat-2 with the type I interferon receptorAssociation of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphataseDependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptorDifferential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transductionCatalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinaseInterferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinaseA region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral stateThe role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses.The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.Dendritic cell regulation of TH1-TH2 development.Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.Homodimerization and intermolecular tyrosine phosphorylation of the Tyk-2 tyrosine kinase.Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.Janus kinases: components of multiple signaling pathways.Structural basis of recognition of interferon-α receptor by tyrosine kinase 2Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction.Three distinct loci on human chromosome 21 contribute to interferon-alpha/beta responsiveness.Alpha-interferon and its effects on signal transduction pathways.Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleostsParamyxovirus accessory proteins as interferon antagonists.Paramyxovirus strategies for evading the interferon response.
P2860
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P2860
Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@ast
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@en
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@nl
type
label
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@ast
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@en
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@nl
prefLabel
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@ast
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@en
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@nl
P2093
P2860
P356
P1476
Direct binding to and tyrosine ...... or by p135tyk2 tyrosine kinase
@en
P2093
J Krolewski
J Mullersman
K Krishnan
O Colamonici
P Domanski
P2860
P304
P356
10.1128/MCB.14.12.8133
P407
P577
1994-12-01T00:00:00Z