JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
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CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunctionInterleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayProtein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling.A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptorsActivation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loopHuman interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity bindingFunctional regions of the mouse interleukin-10 receptor cytoplasmic domainJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.GM-CSF: An immune modulatory cytokine that can suppress autoimmunitySTAM2, a new member of the STAM family, binding to the Janus kinasesChoice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptorsThe conserved box 1 motif of cytokine receptors is required for association with JAK kinasesStat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiationChemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmanninRegions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptorGrowth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signalingPhosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptorBCR-ABL affects STAT5A and STAT5B differentiallyFMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiationThe proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cellsEvidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptorSHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substratesMolecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transductionA region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral stateAlternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.Role of c-Fes in normal and neoplastic hematopoiesis.Association of RACK1 and PKCbeta with the common beta-chain of the IL-5/IL-3/GM-CSF receptor.A cytokine-cytokine interaction in the assembly of higher-order structure and activation of the interleukine-3:receptor complex.Myeloperoxidase gene expression and regulation by myeloid cell growth factors in normal and leukemic cells.Signaling domains of the beta c chain of the GM-CSF/IL-3/IL-5 receptor.A role for extracellular matrix binding receptors in regulating hematopoietic growth factor signaling.The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling.Stoichiometric structure-function analysis of the prolactin receptor signaling domain by receptor chimeras.mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response.Activation of JAK2-V617F by components of heterodimeric cytokine receptorsCytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines.Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled.
P2860
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P2860
JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
JAK2 associates with the beta ...... s the membrane-proximal region
@ast
JAK2 associates with the beta ...... s the membrane-proximal region
@en
JAK2 associates with the beta ...... s the membrane-proximal region
@nl
type
label
JAK2 associates with the beta ...... s the membrane-proximal region
@ast
JAK2 associates with the beta ...... s the membrane-proximal region
@en
JAK2 associates with the beta ...... s the membrane-proximal region
@nl
prefLabel
JAK2 associates with the beta ...... s the membrane-proximal region
@ast
JAK2 associates with the beta ...... s the membrane-proximal region
@en
JAK2 associates with the beta ...... s the membrane-proximal region
@nl
P2093
P2860
P356
P1476
JAK2 associates with the beta ...... s the membrane-proximal region
@en
P2093
A Miyajima
B A Witthuhn
F W Quelle
J D Griffin
R C Inhorn
P2860
P304
P356
10.1128/MCB.14.7.4335
P407
P577
1994-07-01T00:00:00Z