Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction - sprookjes - yvandenbroek - TriplyDB

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

http://www.wikidata.org/entity/Q24617419

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Cytosolic Innate Immune Sensing and Signaling upon Infection Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling The Immune Response in Measles: Virus Control, Clearance and Protective Immunity RIG-I in RNA virus recognition Interferons and viruses: an evolutionary arms race of molecular interactions Influenza virus activation of the interferon system Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA The immunomodulating V and W proteins of Nipah virus determine disease course.Oncolysis by paramyxoviruses: multiple mechanisms contribute to therapeutic efficiency.Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region.Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length.Control of the induction of type I interferon by Peste des petits ruminants virus.Newcastle disease virus infection in chicken embryonic fibroblasts but not duck embryonic fibroblasts is associated with elevated host innate immune response.Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5 Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets.Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist.In vitro inhibition of mumps virus by retinoids.The laboratory of genetics and physiology 2: emerging insights into the controversial functions of this RIG-I-like receptor.Paramyxovirus activation and inhibition of innate immune responses.MDA5 Induces a Stronger Interferon Response than RIG-I to GCRV Infection through a Mechanism Involving the Phosphorylation and Dimerization of IRF3 and IRF7 in CIK Cells Recent advances in understanding viral evasion of type I interferon.Paramyxovirus evasion of innate immunity: Diverse strategies for common targets.Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors.Graf1 Controls the Growth of Human Parainfluenza Virus Type 2 through Inactivation of RhoA Signaling.Manipulation of viral infection by deubiquitinating enzymes: new players in host-virus interactions.La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation Novel Atlantic bottlenose dolphin parainfluenza virus TtPIV-1 clusters with bovine PIV-3 genotype B strains.Modulation of Host Immunity by the Human Metapneumovirus.Paramyxovirus V protein interaction with the antiviral sensor LGP2 disrupts MDA5 signaling enhancement but is not relevant to LGP2-mediated RLR signaling inhibition Innate immune defense defines susceptibility of sarcoma cells to measles vaccine virus-based oncolysis.Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis RNA-virus proteases counteracting host innate immunity.Enhanced growth of influenza A virus by coinfection with human parainfluenza virus type 2.

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P2860

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

http://www.wikidata.org/entity/Q24617419

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

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name

Paramyxovirus V proteins inter ...... dependent interferon induction

@ast

Paramyxovirus V proteins inter ...... dependent interferon induction

@en

Paramyxovirus V proteins inter ...... dependent interferon induction

@nl

type

label

Paramyxovirus V proteins inter ...... dependent interferon induction

@ast

Paramyxovirus V proteins inter ...... dependent interferon induction

@en

Paramyxovirus V proteins inter ...... dependent interferon induction

@nl

prefLabel

Paramyxovirus V proteins inter ...... dependent interferon induction

@ast

Paramyxovirus V proteins inter ...... dependent interferon induction

@en

Paramyxovirus V proteins inter ...... dependent interferon induction

@nl

P1433

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Journal of Virology

P1476

Paramyxovirus V proteins inter ...... dependent interferon induction

@en

P2093

Kay Childs

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors

A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2

The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA

Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response

Activation of MDA5 requires higher-order RNA structures generated during virus infection

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

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3411-3421

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scholarly article

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1940847

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P356

10.1128/JVI.06405-11

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7

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86

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Richard E Randall

Stephen Goodbourn

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2012-02-01T00:00:00Z

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22301134

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3302505

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