TAp63 prevents premature aging by promoting adult stem cell maintenance
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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsThe tumor suppressors p53, p63, and p73 are regulators of microRNA processing complexUltraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin AgingChanging Paradigms in Cranio-Facial Regeneration: Current and New Strategies for the Activation of Endogenous Stem CellsDNA repair and aging: the impact of the p53 familyMolecular mechanism of extrinsic factors affecting anti-aging of stem cellsp53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafishGenomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63A New C-Xyloside induces modifications of GAG expression, structure and functional propertiesΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiationSenescence (ageing) @ 2011Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemiaASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63Role of p63 and the Notch pathway in cochlea development and sensorineural deafnessTP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Regulation of p63 protein stability via ubiquitin-proteasome pathway.TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.Hepatic p63 regulates steatosis via IKKβ/ER stressOCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation.p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes.Impact papers on aging in 2009.TAp63 is a transcriptional target of NF-kappaB.p53/p63/p73 in the epidermis in health and diseaseThe human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformationp63 in skin development and ectodermal dysplasias.TAp63 induces senescence and suppresses tumorigenesis in vivo.p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells.p53 Isoforms: An Intracellular Microprocessor?p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasisTranscription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.p53: the barrier to cancer stem cell formation.Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration.TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiationThe carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells.IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epitheliumWhile p73 is essential, p63 is completely dispensable for the development of the central nervous systemp63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.p53 in stem cells
P2860
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P2860
TAp63 prevents premature aging by promoting adult stem cell maintenance
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
TAp63 prevents premature aging by promoting adult stem cell maintenance
@ast
TAp63 prevents premature aging by promoting adult stem cell maintenance
@en
TAp63 prevents premature aging by promoting adult stem cell maintenance
@nl
type
label
TAp63 prevents premature aging by promoting adult stem cell maintenance
@ast
TAp63 prevents premature aging by promoting adult stem cell maintenance
@en
TAp63 prevents premature aging by promoting adult stem cell maintenance
@nl
prefLabel
TAp63 prevents premature aging by promoting adult stem cell maintenance
@ast
TAp63 prevents premature aging by promoting adult stem cell maintenance
@en
TAp63 prevents premature aging by promoting adult stem cell maintenance
@nl
P2093
P2860
P3181
P1433
P1476
TAp63 prevents premature aging by promoting adult stem cell maintenance
@en
P2093
Carol Prives
Elsa R Flores
Freda D Miller
Jeffrey A Biernaskie
Larysa H Pevny
Maryline Paris
Min Soon Cho
Satrajit Sinha
Xiaohua Su
Young Jin Gi
P2860
P3181
P356
10.1016/J.STEM.2009.04.003
P407
P577
2009-07-01T00:00:00Z