Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment - sprookjes - yvandenbroek - TriplyDB

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer's and Parkinson's Disease Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases The role of iron-induced fibrin in the pathogenesis of Alzheimer's disease and the protective role of magnesium Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease.Effects of diet on brain plasticity in animal and human studies: mind the gap.Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders.A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule.Oligomeric proanthocyanidin protects retinal ganglion cells against oxidative stress-induced apoptosis.Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model.Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications.Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment.Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization.Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging.Recommendations for Development of Botanical Polyphenols as "Natural Drugs" for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment.Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.Plant-derived flavanol (-)epicatechin mitigates anxiety in association with elevated hippocampal monoamine and BDNF levels, but does not influence pattern separation in mice.A mixed grape and blueberry extract is safe for dogs to consume.Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction.Neurogenic Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer's Disease.Natural polyphenols in the management of major depression.Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction.Polyphenols: multipotent therapeutic agents in neurodegenerative diseases.Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update.The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples.Brain metabolism and Alzheimer's disease: the prospect of a metabolite-based therapy.Role of polymer-drug conjugates in organ-specific delivery systems.A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols.Polyphenols Beyond Barriers: A Glimpse into the Brain.Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment.Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols Dietary Polyphenols as Potential Remedy for Dementia.The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans.A Randomized, Double-Blinded, Clinical Trial on Effects of a Vitis vinifera Extract on Cognitive Function in Healthy Older Adults.Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells.Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice.Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis.Beneficial Effect of Flavone Derivatives on Aβ-Induced Memory Deficit Is Mediated by Peroxisome Proliferator-Activated Receptor γ Coactivator 1α: A Comparative Study.

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P2860

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

http://www.wikidata.org/entity/Q24624923

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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type

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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prefLabel

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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JNEUROSCI.6437-11.2012

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Journal of Neuroscience

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Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

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Alice Cheng

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Bing Gong

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Bruce Cooper

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Chungfen Zhang

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Constantine Pavlides

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Daniel Raftery

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David B Teplow

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Elsa M Janle

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G A Nagana Gowda

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Isabel Arrieta-Cruz

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P2860

A synaptic model of memory: long-term potentiation in the hippocampus

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease

Phosphorylated CREB binds specifically to the nuclear protein CBP

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.

The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats.

CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation.

Distribution of [3H]trans-resveratrol in rat tissues following oral administration.

Metabolism of green tea catechins: an overview.

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment.

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5144-50

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10.1523/JNEUROSCI.6437-11.2012

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15

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Giulio Maria Pasinetti

Mario G Ferruzzi

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2012-04-11T00:00:00Z

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223977821

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22496560

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Alzheimer's disease

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