Defective forebrain development in mice lacking gp330/megalin.
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Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formationDelta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neuronsThe adaptor protein ARH escorts megalin to and through endosomesIntegration of endocytosis and signal transduction by lipoprotein receptorsNormal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteinsCytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalinDual roles for the Dab2 adaptor protein in embryonic development and kidney transportCubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epitheliaA review of Donnai-Barrow and facio-oculo-acoustico-renal (DB/FOAR) syndrome: clinical features and differential diagnosisLow-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasisCubilin is an albumin binding protein important for renal tubular albumin reabsorptionThe iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closureMutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromesA focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical developmentThe you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafishAutoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseasesLow Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell FunctionApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseSelenoproteins in nervous system development and functionThe fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal functionGenetic and teratogenic approaches to craniofacial developmentThe transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous systemAlterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac developmentPreferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: a control mechanism for thyroid hormone releaseNHE3 Na+/H+ exchanger supports proximal tubular protein reabsorption in vivoProminin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cellsThe very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro.Rotational imaging optical coherence tomography for full-body mouse embryonic imaging.Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.Holoprosencephaly.Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complexIsoforms of retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liverLoss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development.Cyclopia (synophthalmia) in Smith-Lemli-Opitz syndrome: First reported case and consideration of mechanism.Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes.Behavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouseMutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma
P2860
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P2860
Defective forebrain development in mice lacking gp330/megalin.
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Defective forebrain development in mice lacking gp330/megalin
@nl
Defective forebrain development in mice lacking gp330/megalin.
@ast
Defective forebrain development in mice lacking gp330/megalin.
@en
type
label
Defective forebrain development in mice lacking gp330/megalin
@nl
Defective forebrain development in mice lacking gp330/megalin.
@ast
Defective forebrain development in mice lacking gp330/megalin.
@en
prefLabel
Defective forebrain development in mice lacking gp330/megalin
@nl
Defective forebrain development in mice lacking gp330/megalin.
@ast
Defective forebrain development in mice lacking gp330/megalin.
@en
P2093
P2860
P3181
P356
P1476
Defective forebrain development in mice lacking gp330/megalin.
@en
P2093
A Rohlmann
R E Hammer
S A Armstrong
T E Willnow
P2860
P304
P3181
P356
10.1073/PNAS.93.16.8460
P407
P577
1996-08-01T00:00:00Z