SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine - sprookjes - yvandenbroek - TriplyDB

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

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Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity SIRT1 and Kidney Function Potential Modulation of Sirtuins by Oxidative Stress Evolution and functional cross-talk of protein post-translational modifications Chemical reporters for exploring protein acylation Sirtuins in hematological aging and malignancy Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming Sirtuins, metabolism, and DNA repair Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases Sirtuins in epigenetic regulation Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity Overexpression of SIRT6 in the hippocampal CA1 impairs the formation of long-term contextual fear memory Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin The role of sirtuins in cardiac disease Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and peptide-based inhibitors The role of sirtuins in cellular homeostasis Coupling circadian rhythms of metabolism and chromatin remodelling Defining the orphan functions of lysine acetyltransferases Schistosoma mansoni Sirtuins: characterization and potential as chemotherapeutic targets Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules.A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions.Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.Fatty acylation of proteins: The long and the short of it.Small-molecule allosteric activators of sirtuins.Characterization of physiological defects in adult SIRT6-/- mice A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes.Sirtuins: guardians of mammalian healthspan.The Identification of a SIRT6 Activator from Brown Algae Fucus distichus Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer Epigenetic control of gene function in schistosomes: a source of therapeutic targets?Thiomyristoyl peptides as cell-permeable Sirt6 inhibitors.C. elegans sirtuin SIR-2.4 and its mammalian homolog SIRT6 in stress response.Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins.SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK.JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.Technologies and Challenges in Proteomic Analysis of Protein S-acylation.Depletion of the central metabolite NAD leads to oncosis-mediated cell death.Sirtuins are evolutionarily conserved viral restriction factors.

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SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

http://www.wikidata.org/entity/Q24631433

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2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

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2013年论文

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name

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@ast

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@en

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@nl

type

label

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@ast

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@en

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@nl

prefLabel

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@ast

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@en

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

@nl

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SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

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Bin He

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Eva Ge

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Guillaume Charron

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Hening Lin

http://www.w3.org/2001/XMLSchema#string

Hong Jiang

http://www.w3.org/2001/XMLSchema#string

Howard C Hang

http://www.w3.org/2001/XMLSchema#string

Jintang Du

http://www.w3.org/2001/XMLSchema#string

Quan Hao

http://www.w3.org/2001/XMLSchema#string

Raul Mostoslavsky

http://www.w3.org/2001/XMLSchema#string

Ray Kim

http://www.w3.org/2001/XMLSchema#string

P2860

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

The CCP4 suite: programs for protein crystallography

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

The TNF and TNF receptor superfamilies: integrating mammalian biology

The sirtuin SIRT6 regulates lifespan in male mice

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells

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110-3

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1805084

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10.1038/NATURE12038

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7443

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496

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Carlos Sebastian

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2013-04-04T00:00:00Z

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236103934

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