RGS9-2: probing an intracellular modulator of behavior as a drug target.
about
Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchorsμ-Opioid receptors and regulators of G protein signaling (RGS) proteins: from a symposium on new concepts in mu-opioid pharmacologyR7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaineEmerging Putative Associations between Non-Coding RNAs and Protein-Coding Genes in Neuropathic Pain: Added Value from Reusing Microarray DataProteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysis.Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteinsA conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins.Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transductionSensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior.β-arrestin2 plays permissive roles in the inhibitory activities of RGS9-2 on G protein-coupled receptors by maintaining RGS9-2 in the open conformation.D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions.RGS9-2 modulates sensory and mood related symptoms of neuropathic pain.R7BP modulates opiate analgesia and tolerance but not withdrawal.RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.A unique role of RGS9-2 in the striatum as a positive or negative regulator of opiate analgesiaThe complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatumMacromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.Modulation of pain, nociception, and analgesia by the brain reward center.RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States.Current Concepts on the Physiopathological Relevance of Dopaminergic ReceptorsNucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine.Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease
P2860
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P2860
RGS9-2: probing an intracellular modulator of behavior as a drug target.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
RGS9-2: probing an intracellular modulator of behavior as a drug target
@nl
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@ast
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@en
type
label
RGS9-2: probing an intracellular modulator of behavior as a drug target
@nl
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@ast
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@en
prefLabel
RGS9-2: probing an intracellular modulator of behavior as a drug target
@nl
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@ast
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@en
P2093
P2860
P3181
P1476
RGS9-2: probing an intracellular modulator of behavior as a drug target.
@en
P2093
Barbara J Caldarone
Dimitra Terzi
John R Traynor
Venetia Zachariou
P2860
P304
P3181
P356
10.1016/J.TIPS.2008.11.006
P407
P577
2009-02-09T00:00:00Z