Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
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Association between Parkinson's Disease and Cigarette Smoking, Rural Living, Well-Water Consumption, Farming and Pesticide Use: Systematic Review and Meta-AnalysisCatecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disordersAldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson's diseaseAldehyde dehydrogenase inhibition generates a reactive dopamine metabolite autotoxic to dopamine neuronsOrganochlorine chemicals and neurodegeneration among elderly subjects in Costa RicaPACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in miceEndogenous methanol regulates mammalian gene activityNeurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish EmbryosAldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulationDeterminants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease.Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease.Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling.Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.Involvement of the sodium-calcium exchanger 3 (NCX3) in ziram-induced calcium dysregulation and toxicity.Ocular irritation from product of pesticide degradation among workers in a seed warehouse.Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease.Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase.Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonismEmerging Toxicity Models from Emerging Scientists.Platelet mitochondrial activity and pesticide exposure in early Parkinson's diseaseOligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).Molecular heterogeneity of midbrain dopaminergic neurons--Moving toward single cell resolution.Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stressAldehyde dehydrogenase 2 is associated with cognitive functions in patients with Parkinson's diseasePesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson׳s disease.Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease.DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.Targeting midkine and pleiotrophin signalling pathways in addiction and neurodegenerative disorders: recent progress and perspectives.New insight into neurodegeneration: the role of proteomics.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Of Pesticides and Men: a California Story of Genes and Environment in Parkinson's Disease.Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.Linking Stress, Catecholamine Autotoxicity, and Allostatic Load with Neurodegenerative Diseases: A Focused Review in Memory of Richard Kvetnansky.Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.Base excision repair variants and pesticide exposure increase Parkinson's disease risk.
P2860
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P2860
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@ast
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@en
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@nl
type
label
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@ast
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@en
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@nl
prefLabel
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@ast
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@en
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@nl
P2093
P2860
P3181
P356
P1476
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
@en
P2093
Aaron Lulla
Alvaro Sagasti
Arthur G Fitzmaurice
Jeff M Bronstein
John E Casida
Kelley C O'Donnell
Lisa Barnhill
Mark C Stahl
Myles Cockburn
P2860
P304
P3181
P356
10.1073/PNAS.1220399110
P407
P50
P577
2013-01-08T00:00:00Z