EZH2 methyltransferase and H3K27 methylation in breast cancer - sprookjes - yvandenbroek - TriplyDB

EZH2 methyltransferase and H3K27 methylation in breast cancer

EZH2 methyltransferase and H3K27 methylation in breast cancer

http://www.wikidata.org/entity/Q24633788

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O-GlcNAcylation regulates EZH2 protein stability and function Current Insights into Long Non-Coding RNAs in Renal Cell Carcinoma Post-translational modification-regulated leukocyte adhesion and migration Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications Estrogens in Male Physiology Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives Long non-coding RNA LUCAT1 is associated with poor prognosis in human non-small lung cancer and regulates cell proliferation via epigenetically repressing p21 and p57 expression A nucleosomal approach to inferring causal relationships of histone modifications.Enhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinoma.EZH2 expression in invasive lobular carcinoma of the breast.Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia.Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis To Evaluate Epigenetic Drugs.Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis.Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice.Gene silencing and Polycomb group proteins: an overview of their structure, mechanisms and phylogenetics.Signaling pathway and molecular subgroups of medulloblastoma.Canonical and non-canonical roles of the histone methyltransferase EZH2 in mammary development and cancer.EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma.Extensive Epigenetic Changes Accompany Terminal Differentiation of Mouse Hepatocytes After Birth The JAZF1-SUZ12 fusion protein disrupts PRC2 complexes and impairs chromatin repression during human endometrial stromal tumorogenesis Histone H3.3 mutations: a variant path to cancer.The role of polycomb repressive complexes in biliary tract cancer.Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis.Epigenetic mechanisms of breast cancer: an update of the current knowledge.The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development.EZH2 silencing with RNA interference induces G2/M arrest in human lung cancer cells in vitro.Properties of Native High-Density Lipoproteins Inspire Synthesis of Actively Targeted In Vivo siRNA Delivery Vehicles.Aberrant overexpression of EZH2 and H3K27me3 serves as poor prognostic biomarker for esophageal squamous cell carcinoma patients.Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape.Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population.Conservation and diversification of polycomb repressive complex 2 (PRC2) proteins in the green lineage.Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract.Cell lineage determinants as regulators of breast cancer metastasis.Nicotine induces alteration of H3K27 demethylase UTX in kidney cancer cell.EZH2 promotes E2F-driven SCLC tumorigenesis through modulation of apoptosis and cell-cycle regulation.Nrf2 Transcription Factor Can Directly Regulate mTOR: LINKING CYTOPROTECTIVE GENE EXPRESSION TO A MAJOR METABOLIC REGULATOR THAT GENERATES REDOX ACTIVITY.

P2860

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P2860

EZH2 methyltransferase and H3K27 methylation in breast cancer

http://www.wikidata.org/entity/Q24633788

description

2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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type

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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prefLabel

EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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International Journal of Biological Sciences

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EZH2 methyltransferase and H3K27 methylation in breast cancer

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Kyung Hyun Yoo

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Lothar Hennighausen

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Creative Commons Attribution-NonCommercial-NoDerivatives

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

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59-65

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2282383

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10.7150/IJBS.8.59

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1

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51974397

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22211105

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nuclear protein

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breast neoplasm

neoplastic gene expression regulation

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3226033

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