sameAs
Protein kinase-like domain superfamilySH3-like domain superfamilySH2 domain superfamilySRC;FYN;YES;LYNGPVI:FceRI gamma:FYN:LYNGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYNSrc family tyrosine kinases (SFKs)Src family kinases (SFKs)FYN; LYNGrowth Hormone:Growth Hormone Receptor-JAK2 dimer:LYNGPVI binds Fyn and LynAutophosphorylation of LYN kinaseGrowth hormone receptor binds LynEPOR:JAK2:LYN:IRS2EPOR:p-12Y-JAK2:LYN:IRS2p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2
P527
P688
Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptorRole for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damageCD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling systemLyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cellsInteraction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosisRegulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stressTrafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domainIdentification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screenIntegrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cellsLyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitorsSrc-family kinases in B-cell development and signalingIdentification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signalingMonocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinaseNuclear localization of Lyn tyrosine kinase mediated by inhibition of its kinase activityG protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexesThe Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 associationVav2 is required for cell spreadingSteel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cellsA lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylationTransphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregationGab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-KitTyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsProtein kinase C theta is expressed in mast cells and is functionally involved in Fcepsilon receptor I signalingKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationBANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.Ligand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway.
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين في الإنسان العاقل
@ar
name
LYN proto-oncogene, Src family tyrosine kinase
@en
LYN proto-oncogene, Src family tyrosine kinase
@nl
LYN
@fa
LYN
@fr
LYN
@uk
Tirozinska proteinska kinaza Lyn
@sh
Tyrosinkinase Lyn
@de
yn ennym lane ayds
@en-gb
type
label
LYN proto-oncogene, Src family tyrosine kinase
@en
LYN proto-oncogene, Src family tyrosine kinase
@nl
LYN
@fa
LYN
@fr
LYN
@uk
Tirozinska proteinska kinaza Lyn
@sh
Tyrosinkinase Lyn
@de
yn ennym lane ayds
@en-gb
altLabel
LYN
@en
lck/Yes-related novel protein tyrosine kinase
@en
p53Lyn
@en
p56Lyn
@en
tyrosine-protein kinase Lyn
@en
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
@en
prefLabel
LYN proto-oncogene, Src family tyrosine kinase
@en
LYN proto-oncogene, Src family tyrosine kinase
@nl
LYN
@fa
LYN
@fr
LYN
@uk
Tirozinska proteinska kinaza Lyn
@sh
Tyrosinkinase Lyn
@de
yn ennym lane ayds
@en-gb
P129
P361
P527
P637
P638
P680
P681
P682
P705
P352
P6366
P31
P352
P361
P527
P6366
P637
NP_001104567
XP_011515831
XP_016868904
XP_016868905
P638
P680
P681
P682
P702
P703
P705
ENSP00000428313
ENSP00000428424
ENSP00000428924