A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?
about
Differential association between HERG and KCNE1 or KCNE2KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsKCNE2 and the K (+) channel: the tail wagging the dogMolecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine MyocardiumSubcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heartInherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels.Electrophysiological Characteristics of the LQT2 Syndrome Mutation KCNH2-G572S and Regulation by Accessory Protein KCNE2.In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.HERG1 channelopathiesHERG channel (dys)function revealed by dynamic action potential clamp techniqueRanolazine: ion-channel-blocking actions and in vivo electrophysiological effects.Drug-induced torsades de pointes and implications for drug development.Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of actionBlockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapineInhibition of HERG potassium channels by domiphen bromide and didecyl dimethylammonium bromide.Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channelAnalysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebratesThe phenotype of a KCNQ1 mutation depends on its KCNE partners: is the cardiac slow delayed rectifier (IKs) channel more than a KCNQ1/KCNE1 complex?The hERG potassium channel as a therapeutic target.Effects of MiRP1 and DPP6 beta-subunits on the blockade induced by flecainide of Kv4.3/KChIP2 channels.Cotranslational association of mRNA encoding subunits of heteromeric ion channels.Mechanism of HERG potassium channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride.KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?Modification of K+ channel-drug interactions by ancillary subunits.In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome.Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition.Genotype- and phenotype-guided management of congenital long QT syndrome.Drug-induced hERG block and long QT syndrome.The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome.Potassium-channel mutations and cardiac arrhythmias--diagnosis and therapy.Pharmacogenetics of drug-induced arrhythmias.A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.Cardiac Delayed Rectifier Potassium Channels in Health and Disease.Molecular Pathophysiology of Congenital Long QT Syndrome.The hERG K(+) channel S4 domain L532P mutation: characterization at 37°CDynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes: insights from bifurcation analyses of a mathematical model.Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking.Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia.
P2860
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P2860
A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
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2002年论文
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name
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@ast
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@en
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@nl
type
label
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@ast
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@en
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@nl
prefLabel
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@ast
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@en
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@nl
P2093
P2860
P1476
A comparison of currents carri ...... nt. Is MiRP1 the missing link?
@en
P2093
Denis Chartier
Manjula Weerapura
Ricardo Caballero
Stanley Nattel
Terence E Hébert
P2860
P356
10.1113/JPHYSIOL.2001.013296
P407
P577
2002-04-01T00:00:00Z