Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
about
Crystal structure of the pyridoxal-5'-phosphate-dependent serine dehydratase from human liver3-Phosphoglycerate dehydrogenase deficiency: an inborn error of serine biosynthesisCharacterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesisMolecular characterization of 3-phosphoglycerate dehydrogenase deficiency--a neurometabolic disorder associated with reduced L-serine biosynthesis.Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cellsGenotype directed therapy in murine mismatch repair deficient tumorsTargeting purine and pyrimidine metabolism in human apicomplexan parasitesNucleotide sequence and expression of a cDNA encoding rabbit liver cytosolic serine hydroxymethyltransferase.Requirement of the expression of 3-phosphoglycerate dehydrogenase for traversing S phase in murine T lymphocytes following immobilized anti-CD3 activation.Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization.Serine catabolism regulates mitochondrial redox control during hypoxiaMetabonomics identifies serum metabolite markers of colorectal cancer.The molecular determinants of de novo nucleotide biosynthesis in cancer cells3-Phosphoglycerate dehydrogenase expression is regulated by HOXA10 in murine endometrium and human endometrial cells.Proteomic identification of mitochondrial targets of arginase in human breast cancer.L-serine in disease and developmentMagic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissuesAn epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.Downregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3.Characterization of the formate (for) locus, which encodes the cytosolic serine hydroxymethyltransferase of Neurospora crassaIncreased Expression of PHGDH and Prognostic Significance in Colorectal Cancer.Mouse models to elucidate mechanisms of folate-related cancer pathologies.Genetic variation in the one-carbon transfer pathway and ovarian cancer risk.Phosphoglycerate dehydrogenase: potential therapeutic target and putative metabolic oncogene.Meta-analysis of gene expression profiles identifies differential biomarkers for hepatocellular carcinoma and cholangiocarcinoma.Control analysis of mammalian serine biosynthesis. Feedback inhibition on the final step.Role of Arg-401 of cytosolic serine hydroxymethyltransferase in subunit assembly and interaction with the substrate carboxy group.Influence of Ki-ras-driven oncogenic transformation on the protein network of murine fibroblasts.Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis.A meta-analysis of the C1420T polymorphism in cytosolic serine hydroxymethyltransferase (SHMT1) among Caucasian colorectal cancer populations.Targeting Metabolism for Cancer Therapy.Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene.Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.Dissecting yeast Hog1 MAP kinase pathway using a chemical genetic approach.Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.The Role of His-134, -147, and -150 Residues in Subunit Assembly, Cofactor Binding, and Catalysis of Sheep Liver Cytosolic Serine Hydroxymethyltransferase
P2860
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P2860
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@ast
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@en
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@nl
type
label
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@ast
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@en
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@nl
prefLabel
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@ast
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@en
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@nl
P2093
P2860
P3181
P356
P1476
Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma
@en
P2093
P2860
P2888
P3181
P356
10.1038/BJC.1988.15
P407
P577
1988-01-01T00:00:00Z
P5875
P6179
1034226070