Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
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'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?Celecoxib for osteoarthritisAcetaminophen for osteoarthritisRofecoxib for osteoarthritisCyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expressionAspirin, cyclooxygenase inhibition and colorectal cancerCyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapyDiosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpressionMarine Diterpenoids as Potential Anti-Inflammatory AgentsNSAID therapy effects on healing of bone, tendon, and the enthesisGastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategiesA novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxibPrediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling.Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cellsA free energy based computational pathway from chemical templates to lead compounds: a case study of COX-2 inhibitorsEffect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cellsNSAIDs: gastroprotection or selective COX-2 inhibitor?Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferationReview article: the gastrointestinal safety profile of rofecoxib, a highly selective inhibitor of cyclooxygenase-2, in humansAspirin promotes TFF2 gene activation in human gastric cancer cell linesSafety of a specific COX-2 inhibitor in aspirin-induced asthmaCyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outsDelay in oral mucosal ulcer healing by aspirin is linked to the disturbances in p38 mitogen-activated protein kinase activationBalancing the gastrointestinal benefits and risks of nonselective NSAIDs.Cyclooxygenase inhibition: between the devil and the deep blue seaInhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21How do aspirin and company work? Cyclooxygenases--point of attack of nonsteroidal antirheumaticsSerum deprivation and re-addition: effects on cyclooxygenase inhibitor sensitivity in cultured gliaPostnatal maturation in nitric oxide-induced pulmonary artery relaxation involving cyclooxygenase-1 activityDifferential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro studyEffects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymesModulation of COX-2 expression in peripheral blood cells by increased intake of fruit and vegetables?Kinetic, thermodynamic and statistical studies on the inhibition of adenosine deaminase by aspirin and diclofenacDifferential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cellsA three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitorsFunction of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxin
P2860
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P2860
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@ast
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@en
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@nl
type
label
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@ast
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@en
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@nl
prefLabel
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@ast
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@en
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@nl
P2093
P2860
P3181
P356
P1476
Nonsteroid drug selectivities ...... city: a full in vitro analysis
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.96.13.7563
P407
P577
1999-06-22T00:00:00Z