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Active human immunodeficiency virus protease is required for viral infectivity

Active human immunodeficiency virus protease is required for viral infectivity

http://www.wikidata.org/entity/Q24647696

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Identification and characterization of a novel retroviral-like aspartic protease specifically expressed in human epidermis Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1 A novel self-replicating chimeric lentivirus-like particle Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles Rationale and clinical utility of the darunavir-cobicistat combination in the treatment of HIV/AIDS Current perspectives on HIV-1 antiretroviral drug resistance Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: Insights into the mechanisms of drug resistance 1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir Catalytic Water Co-Existing with a Product Peptide in the Active Site of HIV-1 Protease Revealed by X-Ray Structure Analysis Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants Hydrophobic Core Flexibility Modulates Enzyme Activity in HIV-1 Protease Potent Antiviral HIV-1 Protease Inhibitor GRL-02031 Adapts to the Structures of Drug Resistant Mutants with Its P1′-Pyrrolidinone Ring HIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural Rearrangements Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds P2' Benzene Carboxylic Acid Moiety Is Associated with Decrease in Cellular Uptake: Evaluation of Novel Nonpeptidic HIV-1 Protease Inhibitors Containing P2 bis-Tetrahydrofuran Moiety GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV Carbamylation of N-Terminal Proline Structural Basis of Why Nelfinavir-Resistant D30N Mutant of HIV-1 Protease Remains Susceptible to Saquinavir ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures The aspartic proteases Thioltransferase (glutaredoxin) is detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease

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P2860

Active human immunodeficiency virus protease is required for viral infectivity

http://www.wikidata.org/entity/Q24647696

description

1988 nî lūn-bûn

@nan

1988 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1988 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

1988年の論文

@ja

1988年論文

@yue

1988年論文

@zh-hant

1988年論文

@zh-hk

1988年論文

@zh-mo

1988年論文

@zh-tw

1988年论文

@wuu

name

Active human immunodeficiency virus protease is required for viral infectivity

@ast

Active human immunodeficiency virus protease is required for viral infectivity

@en

Active human immunodeficiency virus protease is required for viral infectivity

@nl

type

label

Active human immunodeficiency virus protease is required for viral infectivity

@ast

Active human immunodeficiency virus protease is required for viral infectivity

@en

Active human immunodeficiency virus protease is required for viral infectivity

@nl

prefLabel

Active human immunodeficiency virus protease is required for viral infectivity

@ast

Active human immunodeficiency virus protease is required for viral infectivity

@en

Active human immunodeficiency virus protease is required for viral infectivity

@nl

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PNAS.85.13.4686

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Active human immunodeficiency virus protease is required for viral infectivity

@en

P2093

E A Emini

http://www.w3.org/2001/XMLSchema#string

E M Scolnick

http://www.w3.org/2001/XMLSchema#string

I S Sigal

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J C Heimbach

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L J Davis

http://www.w3.org/2001/XMLSchema#string

N E Kohl

http://www.w3.org/2001/XMLSchema#string

R A Dixon

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W A Schleif

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P2860

Complete nucleotide sequence of the AIDS virus, HTLV-III

Nucleotide sequence of the AIDS virus, LAV

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells

A structural model for the retroviral proteases.

Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor.

Bovine leukemia virus protease: purification, chemical analysis, and in vitro processing of gag precursor polyproteins

A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins.

Translational readthrough of an amber termination codon during synthesis of feline leukemia virus protease

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

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scholarly article

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4808445

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10.1073/PNAS.85.13.4686

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13

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85

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3290901

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