Rapamycin fed late in life extends lifespan in genetically heterogeneous mice - sprookjes - yvandenbroek - TriplyDB

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

http://www.wikidata.org/entity/Q24647805

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Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans Cholesterol homeostasis: a key to prevent or slow down neurodegeneration Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease SIRT1 negatively regulates the mammalian target of rapamycin Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses OASIS: online application for the survival analysis of lifespan assays performed in aging research SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation Phytochemical modulators of mitochondria: the search for chemopreventive agents and supportive therapeutics Dietary interventions to extend life span and health span based on calorie restriction Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism Strategies for treatment in Alexander disease Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity Extending healthy life span--from yeast to humans Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice Lessons on longevity from budding yeast Stronger is not always better: could a bodybuilding dietary supplement lead to ALS?mTOR is a key modulator of ageing and age-related disease Genome-environment interactions that modulate aging: powerful targets for drug discovery Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer miR-17-92 cluster: ups and downs in cancer and aging The mTOR signalling pathway in human cancer An emerging role for TOR signaling in mammalian tissue and stem cell physiology Autophagy in ageing and ageing-associated diseases Single-gene mutations and healthy ageing in mammals Aging as an event of proteostasis collapse Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy Replicative and chronological aging in Saccharomyces cerevisiae.mTOR: from growth signal integration to cancer, diabetes and ageing Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.mTOR signaling in growth control and disease Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects Developmental Drift and the Role of Wnt Signaling in Aging Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function "Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules

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P2860

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

http://www.wikidata.org/entity/Q24647805

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@ast

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@en

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@nl

type

label

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@ast

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@en

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@nl

prefLabel

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@ast

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@en

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

@nl

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Christy S Carter

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Clinton M Astle

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David E Harrison

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Elizabeth Fernandez

http://www.w3.org/2001/XMLSchema#string

J Erby Wilkinson

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James F Nelson

http://www.w3.org/2001/XMLSchema#string

Kevin Flurkey

http://www.w3.org/2001/XMLSchema#string

Krystyna Frenkel

http://www.w3.org/2001/XMLSchema#string

Marco Pahor

http://www.w3.org/2001/XMLSchema#string

Martin A Javors

http://www.w3.org/2001/XMLSchema#string

P2860

Extension of chronological life span in yeast by decreased TOR pathway signaling

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

TOR signaling in growth and metabolism

An Aging Interventions Testing Program: study design and interim report

Overview of caloric restriction and ageing

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

Extending life: scientific prospects and political obstacles

Genetics: influence of TOR kinase on lifespan in C. elegans

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scholarly article

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554412

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10.1038/NATURE08221

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7253

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460

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2009-07-16T00:00:00Z

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1019246068

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19587680

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2786175

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