neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas - sprookjes - yvandenbroek - TriplyDB

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

http://www.wikidata.org/entity/Q24647944

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Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population Differentiation of insulin-producing cells from human neural progenitor cells Regulation of pancreatic microRNA-7 expression Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets Rfx6 directs islet formation and insulin production in mice and humans IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest Human ASH1 expression in prostate cancer with neuroendocrine differentiation NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system.Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM myc maintains embryonic stem cell pluripotency and self-renewal The MafA transcription factor appears to be responsible for tissue-specific expression of insulin Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity RETRACTED: Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development MafB is required for islet beta cell maturation Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3 Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology β-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas Insulin-secreting β cells require a post-genomic concept Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells Pancreatic β Cell Mass Death Multipotent pancreas progenitors: Inconclusive but pivotal topic Notch Signaling in Pancreatic Development β-Cell MicroRNAs: Small but Powerful Generation of β cells from human pluripotent stem cells: are we there yet?Regenerative medicine in diabetes Pancreatic stem cells remain unresolved Reprogramming pancreatic cells to β cells Which stem cells to repair the endocrine pancreas?Pancreas development in humans Pancreas-specific Cre driver lines and considerations for their prudent use Derivation of insulin-producing beta-cells from human pluripotent stem cells Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis

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P2860

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

http://www.wikidata.org/entity/Q24647944

description

2000 nî lūn-bûn

@nan

2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年学术文章

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2000年学术文章

@zh-cn

2000年学术文章

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2000年学术文章

@zh-my

2000年学术文章

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2000年學術文章

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Proceedings of the National Academy of Sciences of the United States of America

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neurogenin3 is required for th ...... cell lineages of the pancreas

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P2093

A Dierich

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F Guillemot

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M LeMeur

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P2860

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

Notch signalling controls pancreatic cell differentiation

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9

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1607-1611

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scholarly article

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1003617

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10.1073/PNAS.97.4.1607

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P433

4

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97

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Gérard Gradwohl

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2000-02-01T00:00:00Z

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12636948

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10677506

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P921

Aizkuņģa dziedzeris

P932

26482

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