Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway
about
The Beta-amyloid protein of Alzheimer's disease: communication breakdown by modifying the neuronal cytoskeletonDeveloping therapeutic approaches to tau, selected kinases, and related neuronal protein targetsSpatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatmentThe role of mTOR signaling in Alzheimer diseaseMapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsyRapamycin attenuates the progression of tau pathology in P301S tau transgenic miceMammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseaseA circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficitsHyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndromeRoles of tau protein in health and disease.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTORSpecific roles of Akt iso forms in apoptosis and axon growth regulation in neurons.A PEPTIDE UNCOUPLING CRMP-2 FROM THE PRESYNAPTIC Ca(2+) CHANNEL COMPLEX DEMONSTRATES EFFICACY IN ANIMAL MODELS OF MIGRAINE AND AIDS THERAPY-INDUCED NEUROPATHY.Functional variants in DPYSL2 sequence increase risk of schizophrenia and suggest a link to mTOR signalingIncreased protein aggregation in Zucker diabetic fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide.Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice.Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complexThe Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo.Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neuronsNeuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activitiesCyr61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons.The importance of tau phosphorylation for neurodegenerative diseasesRapamycin, Autophagy, and Alzheimer's DiseaseTargeted treatment trials for tuberous sclerosis and autism: no longer a dream.mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors.Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization.The DPYSL2 gene connects mTOR and schizophrenia.GSK3 signalling in neural development.Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex.TSC1/TSC2 signaling in the CNS.Translational research: Rett syndrome and tuberous sclerosis complex.Role of GSK3 Signaling in Neuronal Morphogenesis.Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?Biochemistry and cell biology of tau protein in neurofibrillary degenerationInsulin in the brain: sources, localization and functions.Targeting the mTOR signaling network for Alzheimer's disease therapy.Tau-dependent suppression of adult neurogenesis in the stressed hippocampus.
P2860
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P2860
Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@ast
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@en
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@nl
type
label
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@ast
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@en
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@nl
prefLabel
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@ast
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@en
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@nl
P2860
P356
P1476
Specification of neuronal pola ...... au via the mTOR-p70S6K pathway
@en
P2093
Kenji Sobue
Tsuyoshi Morita
P2860
P304
P356
10.1074/JBC.M109.008177
P407
P577
2009-10-02T00:00:00Z