Modified citrus pectin anti-metastatic properties: one bullet, multiple targets - sprookjes - yvandenbroek - TriplyDB

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

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A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans Galectin-Binding O-Glycosylations as Regulators of Malignancy Anti-cancer activities of pH- or heat-modified pectin Nuclear transport of galectin-3 and its therapeutic implications Metabolic methanol: molecular pathways and physiological roles Human galectin-2 interacts with carbohydrates and peptides non-classically: new insight from X-ray crystallography and hemagglutination Methanol may function as a cross-kingdom signal Galectin-3 is independently associated with cardiovascular mortality in community-dwelling older adults without known cardiovascular disease: The Rancho Bernardo Study Modified citrus pectin reduces galectin-3 expression and disease severity in experimental acute kidney injury Activation of human T-helper/inducer cell, T-cytotoxic cell, B-cell, and natural killer (NK)-cells and induction of natural killer cell activity against K562 chronic myeloid leukemia cells with modified citrus pectin.Degradation of different pectins by fungi: correlations and contrasts between the pectinolytic enzyme sets identified in genomes and the growth on pectins of different origin.Galectin-3: a potential target for cancer prevention.Emerging role of alpha2,6-sialic acid as a negative regulator of galectin binding and function.Pectin matrix as oral drug delivery vehicle for colon cancer treatment Galectins in hematological malignancies.Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling.Galectin-3 as a Potential Target to Prevent Cancer Metastasis.Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis.Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community.Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction.Roles of pectin in biomass yield and processing for biofuels.Chemoprevention of Low-Molecular-Weight Citrus Pectin (LCP) in Gastrointestinal Cancer Cells.Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans Elevated galectin-3 precedes the development of CKD The inhibitory effects of a rhamnogalacturonan I (RG-I) domain from ginseng pectin on galectin-3 and its structure-activity relationship.The role of galectins in colorectal cancer progression.Atomic force microscopy as a nanoscience tool in rational food design.The sweet side of tumor immunotherapy.Galectin-3 inhibitors: a patent review (2008-present).Galectin-3 expressed on different lung compartments promotes organ specific metastasis by facilitating arrest, extravasation and organ colonization via high affinity ligands on melanoma cells.Over expression of galectin-3 associates with short-term poor prognosis in stage II colon cancer.Comparative studies on the anti-tumor activities of high temperature- and pH-modified citrus pectins.Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice.Synergistic and additive effects of modified citrus pectin with two polybotanical compounds, in the suppression of invasive behavior of human breast and prostate cancer cells.Combination effect of PectaSol and Doxorubicin on viability, cell cycle arrest and apoptosis in DU-145 and LNCaP prostate cancer cell lines.PectaSol-C modified citrus pectin induces apoptosis and inhibition of proliferation in human and mouse androgen-dependent and- independent prostate cancer cells.The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells.Physicochemical properties of modified citrus pectins extracted from orange pomace.Faba bean hulls as a potential source of pectin.Galectin-3 and new-onset CKD: marker or mediator?

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P2860

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

http://www.wikidata.org/entity/Q24651188

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2009 nî lūn-bûn

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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年論文

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2009年論文

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2009年论文

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Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

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Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

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J.CARRES.2008.08.038

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Carbohydrate Research

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Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

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Avraham Raz

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Vladislav V Glinsky

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P2860

NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin

Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation

Dissemination and growth of cancer cells in metastatic sites

Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs.

Galectins in cell growth and apoptosis.

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks.

Galectin-3 protects human breast carcinoma cells against nitric oxide-induced apoptosis: implication of galectin-3 function during metastasis.

Galectin-3 induces endothelial cell morphogenesis and angiogenesis

Galectin-3 as a potential therapeutic target in tumors arising from malignant endothelia.

On the role of galectin-3 in cancer apoptosis.

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