Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis - sprookjes - yvandenbroek - TriplyDB

Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis

Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis

http://www.wikidata.org/entity/Q24651212

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Effects of different tissue microenvironments on gene expression in breast cancer cells Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.Defining the endpoints: how to measure the efficacy of drugs that are active against central nervous system metastases.Current approaches to the treatment of metastatic brain tumours.Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis.Translational research in brain metastasis is identifying molecular pathways that may lead to the development of new therapeutic strategies.Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model Cerebral Gluconeogenesis and Diseases.Integrative genomics identifies gene signature associated with melanoma ulceration.Techniques to monitor glycolysis.Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds.Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.Gene signatures of breast cancer progression and metastasis.The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain Opposing effects of pigment epithelium-derived factor on breast cancer cell versus neuronal survival: implication for brain metastasis and metastasis-induced brain damage.The biology of brain metastases-translation to new therapies The molecular biology of brain metastasis Molecular aspects of breast cancer metastasis to the brain.Identification of pigment epithelium-derived factor protein forms with distinct activities on tumor cell lines.Prognostic Significance of the Metabolic Marker Hexokinase-2 in Various Solid Tumors: A Meta-Analysis.Relevance of PTEN loss in brain metastasis formation in breast cancer patients Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells Pazopanib inhibits the activation of PDGFRβ-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells Clinical significance of KISS1 protein expression for brain invasion and metastasis.Learning subgroup-specific regulatory interactions and regulator independence with PARADIGM.Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma.Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer The prognostic effect of DDX3 upregulation in distant breast cancer metastases.Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer.Breast cancer brain metastases: a review of the literature and a current multidisciplinary management guideline.Hexokinase 2 enhances the metastatic potential of tongue squamous cell carcinoma via the SOD2-H2O2 pathway.Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2.Targeting metabolic remodeling in glioblastoma multiforme.Brain metastases as preventive and therapeutic targets.Microenvironment determinants of brain metastasis.In vivo animal models for studying brain metastasis: value and limitations.Role of the blood-brain barrier in the formation of brain metastases.

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Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis

http://www.wikidata.org/entity/Q24651212

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Molecular Cancer Research

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Analyses of resected human bra ...... exokinase 2 and poor prognosis

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Diane Palmieri

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H Maximilian Mehdorn

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Maria J Merino

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Patricia S Steeg

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P2860

Genes that mediate breast cancer metastasis to the brain

Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.

Mammalian hexokinases and their abnormal expression in cancer.

Breast cancer metastasis to the central nervous system

Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells.

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.

Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluro-2-deoxy-D-glucose positron emission tomography.

Stable RNA interference of hexokinase II gene inhibits human colon cancer LoVo cell growth in vitro and in vivo.

CNS metastases in breast cancer.

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